495414

1-Oleoyl-2-acetyl-sn-glycerol

Cell-permeable diacylglycerol analog that activates Ca²⁺-dependent protein kinase C.

• Synonyme(s) : 1-Oleoyl-2-acetyl-sn-glycerol, OAG, PKC Activator III
• Formule empirique (notation de Hill): C₂₃H₄₂O₅
• Numéro CAS: 86390-77-4
• Poids moléculaire : 398.58
• Numéro MDL: MFCD00166985
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥97% (HPLC)
• Forme: oil
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Solubilité: DMSO: soluble; ethanol: soluble
• Format: neat
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• InChI: 1S/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)27-20-22(19-24)28-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10-/t22-/m0/s1
• Clé InChI: PWTCCMJTPHCGMS-YRBAHSOBSA-N

Description

Description générale

Cell-permeable diacylglycerol analog that activates Ca²⁺-dependent protein kinase C. Also a stimulator of secretion and aggregation in blood platelets.

Note: 1 set = 10 x 500 µg.

Actions biochimiques/physiologiques

Cell permeable: yes

Primary Target
Ca2+-dependent protein kinase C

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Standard Handling (A)

Reconstitution

Unstable in solution; reconstitute just prior to use. The material can be dissolved in chloroform, aliquoted, dried under a stream of nitrogen, and stored at -20°C.

Autres remarques

Florin-Christensen, J. 1993. Biochem. J.289, 783.
Benz, I., et al. 1992. J. Membr. Biol. 130, 183.
Haeffner, E.W., and Wittmann, U. 1992. J. Lipid Mediat.5, 237.
Gilmore, T., and Martin, G.S. 1983. Nature306, 487.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable