487920

S-Nitrosoglutathione

≥95% (HPLC), solid, nitric oxide carrier, Calbiochem^®

• Synonyme(s) : S-Nitrosoglutathione, GSNO, SNOG
• Formule empirique (notation de Hill): C₁₀H₁₆N₄O₇S
• Numéro CAS: 57564-91-7
• Poids moléculaire : 336.32
• Numéro MDL: MFCD00214341
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• product name: S-Nitrosoglutathione, A utility carrier of nitric oxide.
• Niveau de qualité: 100
• Pureté: ≥95% (HPLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated (hygroscopic); protect from light
• Couleur: pink
• Solubilité: water: 10 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• InChI: 1S/C10H16N4O7S/c11-5(10(19)20)1-2-7(15)13-6(4-22-14-21)9(18)12-3-8(16)17/h5-6H,1-4,11H2,(H,12,18)(H,13,15)(H,16,17)(H,19,20)/t5-,6-/m0/s1
• Clé InChI: HYHSBSXUHZOYLX-WDSKDSINSA-N

Description

Description générale

A utility carrier of nitric oxide. Breaks down at physiological pH to produce nitric oxide. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.

A utility carrier of nitric oxide. Breaks down to produce nitric oxide and a glutathione radical at pH 7.4. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
A utility carrier of nitric oxide

Product does not compete with ATP.

Reversible: no

Conditionnement

Packaged under inert gas

Avertissement

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C or for up to 2 h at 4°C.

Reconstitute in cold distilled H₂O (4°C) free of divalent cations other than Ca²⁺.

Autres remarques

Sandau, K., et al. 1996. Cell Signal.8, 173.
Askew, S.C. 1995. Bioorg. Med. Chem.3, 1.
Fehsel, K., et al. 1995. J. Immunol.155, 2858.
de Belder, A.J., et al. 1994. Cardiovasc. Res.28, 691.
Sexton, D.J., et al. 1994. Photochem. Photobiol.59, 463.
Singh, R.J., et al. 1994. FEBS Lett. 360, 47.
Merryman, P.F., et al. 1993. Arthritis Rheum.36, 1414.
Park, J.W., et al. 1993. Biochem. Mol. Biol. Int.30, 885.
Radomski, M.W., et al. 1992. Br. J. Pharmacol.107, 745.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3