454582
Anti-NMDAR 2B (984-1104) Rabbit pAb
lyophilized, Calbiochem®
Synonyme(s) :
Anti-N-Methyl-D-Aspartate Receptor 2B-Subunit
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About This Item
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.43
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
purified antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Forme
lyophilized
Ne contient pas
preservative
Espèces réactives
rat, fish, mouse, human
Fabricant/nom de marque
Calbiochem®
Conditions de stockage
OK to freeze
Isotype
IgG
Conditions d'expédition
ambient
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
Description générale
Immunoaffinty purified rabbit polyclonal antibody. Recognizes the ~180 kDa NMDAR2B subunit of the NMDA receptor.
Recognizes the ~180 kDa NMDA receptor NR2B subunit.
This Anti-NMDAR 2B (984-1104) Rabbit pAb is validated for use in Immunoblotting, Immunohistochemistry, Immunoprecipitation for the detection of NMDAR 2B (984-1104).
Immunogène
Rat Brain
a recombinant fusion protein consisting of amino acids 984-1104 of rat brain NMDAR 2B-subunit
Application
Immunoblotting (1:1000)
Immunohistochemistry (1:1000-1:2000)
Immunoprecipitation (see comments)
Immunohistochemistry (1:1000-1:2000)
Immunoprecipitation (see comments)
Avertissement
Toxicity: Standard Handling (A)
Forme physique
Lyophilized from 5 mM ammonium bicarbonate.
Reconstitution
Reconstitute in 50 µl PBS. Following reconstitution, aliquot and freeze (-20°C). Avoid freeze thaw cycles of reconstituted solution.
Autres remarques
Does not cross-react with NMDAR2A or NMDAR2C. Please refer to the certificate of analysis for lot-specific immunoprecipitation volume. Variables associated with assay conditions will dictate the proper working dilution.
Wang, Y.H., et al. 1995. J. Neurochem.65, 176.
Petralia, R.S., et al. 1994. J. Neurosci.14, 6102.
Ishii, T., et al. 1993. J. Biol. Chem.268, 2836.
Monyer, H., et al. 1992. Nature256, 1217.
Petralia, R.S., et al. 1994. J. Neurosci.14, 6102.
Ishii, T., et al. 1993. J. Biol. Chem.268, 2836.
Monyer, H., et al. 1992. Nature256, 1217.
Informations légales
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Ainhoa Plaza-Zabala et al.
Neuroscience letters, 557 Pt B, 101-106 (2013-11-23)
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Carrie R Ferrario et al.
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We previously showed that the time-dependent intensification ("incubation") of cue-induced cocaine seeking after withdrawal from extended-access cocaine self-administration is accompanied by accumulation of Ca(2+)-permeable AMPA receptors (CP-AMPARs) in the rat nucleus accumbens (NAc). These results suggest an enduring change in
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Clinical studies on patients with stress-related neuropsychiatric disorders reported functional and morphological changes in brain areas where glutamatergic transmission is predominant, including frontal and prefrontal areas. In line with this evidence, several preclinical works suggest that glutamate receptors are targets
Carrie R Ferrario et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 35(3), 818-833 (2009-11-20)
alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionate receptor (AMPAR) surface expression in the nucleus accumbens (NAc) is enhanced after withdrawal from repeated cocaine exposure. However, it is unclear whether this contributes to the expression of locomotor sensitization and whether similar changes can be observed in other
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