371720
Anti-Giα-1-Subunit, Internal (159-168) Rabbit pAb
liquid, Calbiochem®
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About This Item
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
diluted serum
Type de produit anticorps
primary antibodies
Clone
polyclonal
Forme
liquid
Ne contient pas
preservative
Espèces réactives
mouse
Fabricant/nom de marque
Calbiochem®
Conditions de stockage
OK to freeze
avoid repeated freeze/thaw cycles
Isotype
IgG
Conditions d'expédition
wet ice
Température de stockage
−70°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
mouse ... Gnai1(14677)
Description générale
Anti-Giα-1-Subunit, Internal (159-168), rabbit polyclonal, recognizes Giα-1 subunit. Does not cross-react with Giα-2, Giα-3, Goα, or Gsα subunits. It is validated for use in Western blotting.
Rabbit polyclonal antibody supplied as diluted serum. Recognizes Giα-1 subunit.
Recognizes Giα-1 subunit. Does not cross-react with Giα-2, Giα-3, Goα, or Gsα subunits.
Immunogène
a synthetic peptide (LDRIAQPNYI) corresponding to amino acids 159-168 of mouse Giα-1, conjugated to KLH
Application
Immunoblotting (1:1000)
Avertissement
Toxicity: Standard Handling (A)
Forme physique
Serum diluted in 140 mM NaCl, 100 mM potassium phosphate, pH 7.5.
Reconstitution
Following initial thaw, aliquot and freeze (-70°C).
Autres remarques
Does not cross-react with Giα-2, Giα-3, Goα, or Gsα subunits. The specificity and cross-reactivity were confirmed with lysates from separate cultures of bacteria transfected with the genes for Giα-1, Giα-2, Giα-3, Goα and Gsα. Variables associated with assay conditions will dictate the proper working dilution.
Kumar, R., et al. 1994. J. Mol. Cell. Cardiol.26, 1537.
Mumby, S.M., and Gilman, A.G. 1991. Methods Enzymol.195, 215.
Goldsmith, P.P., et al. 1987. J. Biol. Chem.262, 14683.
Mumby, S.M., and Gilman, A.G. 1991. Methods Enzymol.195, 215.
Goldsmith, P.P., et al. 1987. J. Biol. Chem.262, 14683.
Informations légales
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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PloS one, 12(1), e0169609-e0169609 (2017-01-11)
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H-D Yan et al.
British journal of pharmacology, 139(3), 605-615 (2003-06-06)
(1) The effects on the whole-cell carbachol-induced muscarinic cationic current (mIcat) of antibodies against the alpha-subunits of various G proteins, as well as the effect of a Gbetagamma subunit, were studied in single guinea-pig ileal smooth muscle cells voltage-clamped at
Yatin M Patel et al.
Blood, 101(12), 4828-4835 (2003-03-01)
We have examined platelet functional responses and characterized a novel signaling defect in the platelets of a patient suffering from a chronic bleeding disorder. Platelet aggregation responses stimulated by weak agonists such as adenosine diphosphate (ADP) and adrenaline were severely
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Using a Leydig tumor cell line (MA-10) transiently transfected with the human lutropin receptor (hLHR) and mutants thereof, we examined the identity of the G proteins activated by the agonist-engaged hLHR-wild type (wt) and by three of its naturally occurring
Shannon M Gifford et al.
The Journal of endocrinology, 190(2), 373-384 (2006-08-11)
Uterine artery endothelial cells (UAEC) derived from pregnant (P-UAEC) and nonpregnant (NP-UAEC) ewes retain pregnancy-specific differences in cell signaling as well as vasodilator production through passage 4. In particular, when P- and NP-UAEC are stimulated with ATP over a 2.5
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