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Parteck® MXP (Polyvinyl alcohol 3-82)

EMPROVE® ESSENTIAL, Ph. Eur.

Fabrication pharma

Synonyme(s) :

Parteck® Polyvinyl alcohol, PVA, Polyvinyl alcohol

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About This Item

Formule linéaire :
(C2H4O)n
Numéro CAS:
9002-89-5
Numéro MDL:
MFCD00081922
Code UNSPSC :
12352104

Agence

Ph. Eur.

Niveau de qualité

500

Gamme de produits

EMPROVE® ESSENTIAL

Forme

powder

Application(s)

pharmaceutical
solid formulation
solubility enhancement

Température de stockage

15-25°C

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

Clé InChI

IMROMDMJAWUWLK-UHFFFAOYSA-N

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Catégories apparentées

Description générale

With a lower degree of hydrolysis along the PVA chain, Parteck® MXP 3-82 Polyvinyl alcohol is especially beneficial in forming strong interac­tions with hydrophobic drug molecules – in the solid state and in solution. Due to this, Parteck® MXP 3-82 excipient has very high capabilities as a precipitation inhibitor and can maintain high levels of supersaturation for physiologi­cally relevant timescales. As a result, Parteck® MXP 3-82 Polyvinyl alcohol can provide solubility enhancement for even the most challenging molecules.

Application

Parteck® MXP 3-82 is a PVA-based excipient that is used in Hot Melt Extrusion for Solubility Enhancement in oral solid dosage forms.

Caractéristiques et avantages

  • Superior supersaturation performance via precipitation inhibition
  • High thermostability up to 250°C, extending the potential application range
  • Stable high drug loads and suitability with a broad range of APIs
  • Flexible release kinetics
  • Compatible with several downstream processing capabilities, like direct compression, continuous manufacturing, thin film extrusion and 3D printing
  • Optimized powder properties for excellent performance in the HME process
  • Suitable polymer properties for HME, spray drying and 3D printing processes

Informations légales

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

No data available

Point d'éclair (°C)

No data available

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Articles

Solid Formulation Development Using Melt-based 3D Printing Technologies

3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

Solid Formulation Development Using Melt-based 3D Printing Technologies

3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

Solid Formulation Development Using Melt-based 3D Printing Technologies

3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

Solid Formulation Development Using Melt-based 3D Printing Technologies

3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

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Contenu apparenté

3D Printed Precision: Selective Laser Sintering for Oral Drug Delivery

For selective laser sintering (SLS) polymers are needed for a successful workflow and selection of the best approach requires consideration of several factors.

3D Printed Precision: Selective Laser Sintering for Oral Drug Delivery

For selective laser sintering (SLS) polymers are needed for a successful workflow and selection of the best approach requires consideration of several factors.

3D Printed Precision: Selective Laser Sintering for Oral Drug Delivery

For selective laser sintering (SLS) polymers are needed for a successful workflow and selection of the best approach requires consideration of several factors.

3D Printed Precision: Selective Laser Sintering for Oral Drug Delivery

For selective laser sintering (SLS) polymers are needed for a successful workflow and selection of the best approach requires consideration of several factors.

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