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Key Documents

1.09249

Sigma-Aldrich

Mayer′s hemalum solution

for microscopy

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About This Item

Code UNSPSC :
41116121
Nomenclature NACRES :
NA.41

Niveau de qualité

400

Forme

liquid

IVD

for in vitro diagnostic use

Technique(s)

microbe id | staining: suitable

Densité

1.05 g/cm3 at 20 °C

Application(s)

clinical testing
diagnostic assay manufacturing
hematology
histology

Température de stockage

15-25°C

Catégories apparentées

Description générale

Mayer′s hemalum solution - for microscopy, is used in hematoxylin-eosin staining (H&E), which is the most widely used histological staining technique. Nuclear staining is achieved using ready-to-use staining solutions, such as Mayer′s hemalum solution or Hematoxylin solution modified according to Gil III (Product number 1.05174). These solutions do not need to be filtrated prior use and the dye is oxidized in a controlled manner, which renders the results robust and allows a brilliant differentiation of the stained structures. Counterstaining of i.e. for proteins, collagen, keratin, intercellular substances. can be performed with Eosin Y solution 0.5 %, alcoholic (Product number 1.02439)or Eosin Y solution 0.5 % aqueous (Product number 1.09844).
The 500 ml bottle is sufficient for 1500 stainings. It is registered as IVD and CE certified product and can be used for clinical diagnostics. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Remarque sur l'analyse

Suitability for microscopy (Tissue section): passes test
Nuclei: dark blue to dark violet
Cytoplasm: pink to red
intercellular substances: pink to red
Erythrocytes: yellow to orange

Pictogrammes

Exclamation markHealth hazard
GHS07,GHS08

Mention d'avertissement

Warning

Mentions de danger

H302 - H319 - H373

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT RE 2 Oral

Organes cibles

Kidney

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Mare Mechelinck et al.
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Gangqi Wang et al.
Cells, 9(4) (2020-04-03)
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Matthias Schnetz et al.
Cancers, 12(3) (2020-02-29)
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José Rivas et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(6), 7847-7865 (2020-04-18)
Transient receptor potential melastatin 4 (TRPM4) is a Ca2+ -activated nonselective cationic channel that regulates cell migration and contractility. Increased TRPM4 expression has been related to pathologies, in which cytoskeletal rearrangement and cell migration are altered, such as metastatic cancer.

Contenu apparenté

Histologie / Histopathologie

Apprenez-en davantage sur le caractère critique de la coloration de tissus biologiques pour la recherche et la biologie médicale en utilisant des colorants standards et spéciaux.

Histologie / Histopathologie

Apprenez-en davantage sur le caractère critique de la coloration de tissus biologiques pour la recherche et la biologie médicale en utilisant des colorants standards et spéciaux.

Histology / Histopathology

Learn about the criticality of biological tissue staining for research and clinical pathology using standard and special stains and dyes.

Histology / Histopathology

Learn about the criticality of biological tissue staining for research and clinical pathology using standard and special stains and dyes.

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