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Key Documents

09-814

Sigma-Aldrich

Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25)

serum, from rabbit

Synonyme(s) :

dimethyl-arginine, asymmetric

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

serum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

mouse

Réactivité de l'espèce (prédite par homologie)

rat (based on 100% sequence homology), human (based on 100% sequence homology)

Technique(s)

western blot: suitable

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Description générale

Asymmetrical dimethlarginine (ADMA) is an endogenous, L-arginine metabolite arising from the proteolysis of methylated arginine containing proteins and is a known inhibitor of nitric oxide synthase (NOS). In various studies, ADMA has been observed as having a regulatory role in cell motility and the actin cytoskeleton. Elevated levels of ADMA are associated with sporadic FSGS, coronary artery disease, hypertension, peripheral arterial occlusive disease, obesity, stroke, preeclampsia, and cardiovascular mortality/morbidity in patients with diabetic nephropathy.

Spécificité

This antibody recognizes dimethylated arginines.

Immunogène

KLH-conjugated linear peptide containing asymmetric dimethyl-arginine-glycine repeats.

Application

Detect dimethyl-Arginine using this Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) validated for use in WB.

Qualité



µ

Description de la cible

Multiple. This antibody detects proteins containing asymmetrical dimethylated arginines.

Remarque sur l'analyse


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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

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Nucleic acids research, 50(4), 2005-2018 (2022-02-10)
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