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Merck
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Key Documents

07-790

Sigma-Aldrich

Anti-phospho-PKCα (Ser657/Tyr658) Antibody

Upstate®, from rabbit

Synonyme(s) :

PRKCA, PKC-alpha, PKCA, PRKACA

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

human, rat, rabbit

Fabricant/nom de marque

Upstate®

Technique(s)

ELISA: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

NM_002737.2

Numéro d'accès UniProt

P17252

Conditions d'expédition

dry ice

Informations sur le gène

human ... PRKCA(5578)

Spécificité

Recognizes phospho-PKCα (Ser657/Tyr658). This sequence is similar to PKCβI (Ser661/Tyr662) and PKCγ (Thr674/Tyr675).

Immunogène

KLH conjugated peptide corresponding to amino acid region encompassing the human phospho-PKCα (Ser657/Tyr658).

Application

Anti-phospho-PKCα (Ser657/Tyr658) Antibody detects level of phospho-PKCα (Ser657/Tyr658) & has been published & validated for use in ELISA, IP & WB.
Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry

Qualité

Routinely evaluated by immunoblot.

Description de la cible

82 kDa

Forme physique

ImmunoAffinity Purified

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Phosphorylated HSP27 modulates the association of phosphorylated caldesmon with tropomyosin in colonic smooth muscle
Somara, Sita and Bitar, Khalil N
American Journal of Physiology: Gastrointestinal and Liver Physiology, 291, G630-G639 (2006)
Samantha J Borland et al.
Cardiovascular research, 113(13), 1639-1652 (2017-10-11)
Vascular calcification is a major cause of morbidity and mortality. Fibroblast growth factor-2 (FGF-2) plays an instructive role in osteogenesis and bone development, but its role in vascular calcification was unknown. Therefore, we investigated the involvement of FGF-2 in vascular
Zangbéwendé Guy Ouédraogo et al.
Brain pathology (Zurich, Switzerland), 26(1), 18-30 (2015-03-05)
Radiotherapy is an essential component of glioma standard treatment. Glioblastomas (GBM), however, display an important radioresistance leading to tumor recurrence. To improve patient prognosis, there is a need to radiosensitize GBM cells and to circumvent the mechanisms of resistance caused
Haoran Miao et al.
Oncology reports, 48(6) (2022-10-26)
Current investigations suggest that pigment epithelial‑derived factor (PEDF) can mediate the progression of non‑small cell lung cancer (NSCLC) by regulating autophagy. However, the underlying mechanisms associated with autophagy remain poorly elucidated. The aim of the present study was to investigate
Moona Huttunen et al.
Cellular microbiology, 19(3) (2016-10-21)
We have demonstrated previously that the human picornavirus Echovirus 1 (EV1) triggers an infectious internalization pathway that follows closely, but seems to stay separate, from the epidermal growth factor receptor (EGFR) pathway triggered by epidermal growth factor (EGF). Here, we
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