07-104

Anti-IGF2 mRNA-binding protein 3 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : IGF II mRNA binding protein 3, IGF-II mRNA-binding protein 3, IGF2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, KH domain-containing protein overexpressed in cancer, VICKZ family member 3, insulin-like growth factor 2 mRN
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human, mouse, canine
• Réactivité de l'espèce (prédite par homologie): rhesus monkey (based on 100% sequence homology), dog (based on 100% sequence homology), horse (based on 100% sequence homology), chimpanzee (based on 100% sequence homology)
• Technique(s): western blot: suitable
• Numéro d'accès NCBI: NP_006538
• Numéro d'accès UniProt: O00425
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... IGF2BP3(10643)

Description

Description générale

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5′ UTR of the insulin-like growth factor 2 leader 3 mRNA and may repress translation of insulin-like growth factor 2 during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq].

Spécificité

This antibody recognizes IGF2 mRNA-binding protein 3 at the C-terminus.

Immunogène

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to human IGF2 mRNA-binding protein 3 at and around the C-terminus.

Application

Research Category
Apoptosis & Cancer

Research Sub Category
Growth Factors & Receptors

This Anti-IGF2 mRNA-binding protein 3 Antibody is validated for use in WB for the detection of IGF2 mRNA-binding protein 3.

Western Blot (SNAP ID) Analysis: 2 µg/mL from a previous lot detected IGF2 mRNA-binding protein 3 on 10 µg of Hek293 cell lysate.

Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP.

Qualité

Evaluated by Western Blot in Hek293 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected IGF2 mRNA-binding protein 3 on 10 µg of Hek293 cell lysate.

Description de la cible

64 kDa was observed. Predicted to cross-react with all the Isoforms of IGF2BP3.

Forme physique

Affinity purified

Purified rabbit serum in PBS with 0.09% azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Hek293 cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable