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05-855R

Sigma-Aldrich

Anti-GluR1 Antibody, Recombinant, rabbit monoclonal

Upstate®, from rabbit

Synonyme(s) :

Anti-GluA1, Anti-GluR-1, Anti-GluR-A, Anti-GluR-K1, Anti-GluR1

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

monoclonal

Espèces réactives

rat, mouse

Fabricant/nom de marque

Upstate®

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Numéro d'accès NCBI

NP_000818.2

Numéro d'accès UniProt

P42261

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

mouse ... Gria1(14799)
rat ... Gria1(50592)

Spécificité

Cat. # 05-855R recognizes the monomer and dimer of GluR1.
Reactivity with other species has not been determined.

Application

Anti-GluR1 Antibody, Recombinant is an antibody against GluR1 for use in WB, IH.
Immunohistochemistry: Cat. # 05-855R can detect GluR1 in rat brain tissue at 1:250 dilution.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Qualité

Routinely evaluated by western blot on rat brain microsomal lysate.

Description de la cible

Monomer at 106 kDa and Dimer at 200 kDa

Forme physique

Format: Purified
Purified Antibody in 0.01M Tris-Glycine, 0.15M NaCl, pH 7.4, 0.05% NaN3with 40% glycerol.

Stockage et stabilité

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Remarque sur l'analyse

Control
Rat brain microsomal lysate

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Réf. du produit
Description
Tarif

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

GluA1 in central amygdala increases pain but inhibits opioid withdrawal-induced aversion.
You-Qing Cai et al.
Molecular pain, 16, 1744806920911543-1744806920911543 (2020-03-13)
Rachel Thomas et al.
The Journal of biological chemistry, 298(8), 102245-102245 (2022-07-15)
Cortical glutamate and midbrain dopamine neurotransmission converge to mediate striatum-dependent behaviors, while maladaptations in striatal circuitry contribute to mental disorders. However, the crosstalk between glutamate and dopamine signaling has not been entirely elucidated. Here we uncover a molecular mechanism by
Gajanan P Shelkar et al.
The international journal of neuropsychopharmacology, 24(11), 907-919 (2021-08-08)
Enhancement of N-methyl-D-aspartate (NMDA) receptor function using glycine-site agonist D-cycloserine is known to facilitate fear extinction, providing a means to augment cognitive behavioral therapy in anxiety disorders. A novel class of glycine-site agonists has recently been identified, and we have
Jane K Schröder et al.
Cells, 12(13) (2023-07-14)
Circadian rhythms in behavior and physiology such as rest/activity and hormones are driven by an internal clock and persist in the absence of rhythmic environmental cues. However, the period and phase of the internal clock are entrained by the environmental
Central amygdala GluA1 facilitates associative learning of opioid reward.
Cai, YQ; Wang, W; Hou, YY; Zhang, Z; Xie, J; Pan, ZZ
The Journal of Neuroscience null
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