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Merck
Toutes les photos(1)

Principaux documents

05-850

Sigma-Aldrich

Anti-p68 Antibody, clone204

clone 204, Upstate®, from mouse

Synonyme(s) :

Anti-G17P1, Anti-HUMP68, Anti-p68

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

204, monoclonal

Espèces réactives

human, rat, mouse

Fabricant/nom de marque

Upstate®

Technique(s)

western blot: suitable

Isotype

IgG1

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... DDX5(1655)

Description générale

Also known as DDX5, p68 is a DEAD-box ATPase and RNA splicing factor.

Spécificité

p68

Immunogène

Purified T antigen-related protein from Ad2+ ND2 virus-infected HeLa cells.

Application

Detect p68 with Anti-p68 Antibody, clone204 (Mouse Monoclonal Antibody), that has been shown to work in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

RNA Binding Protein (RBP)

Qualité

Routinely evaluated by immunoblot of nuclear extracts from HeLa cells

Description de la cible

68kDa

Forme physique

Format: Purified
Protein G Purified

Stockage et stabilité

2 years at -20°C

Remarque sur l'analyse

Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

M J Ford et al.
Nature, 332(6166), 736-738 (1988-04-21)
The p68 protein is a highly conserved nuclear antigen that is thought to be important in the regulation of cell growth and division. It is found in dividing cells of all mammals and amphibians tested, but not in quiescent cells.
Raphaël Métivier et al.
Cell, 115(6), 751-763 (2003-12-17)
Transcriptional activation of a gene involves an orchestrated recruitment of components of the basal transcription machinery and intermediate factors, concomitant with an alteration in local chromatin structure generated by posttranslational modifications of histone tails and nucleosome remodeling. We provide here
Zhi-Ren Liu
Molecular and cellular biology, 22(15), 5443-5450 (2002-07-09)
Modulation of the interaction between U1 snRNP and the 5' splice site (5'ss) is a key event that governs 5'ss recognition and spliceosome assembly. Using the methylene blue-mediated cross-linking method (Z. R. Liu, A. M. Wilkie, M. J. Clemens, and
Kengo Takeda et al.
International journal of molecular sciences, 25(7) (2024-04-13)
Chronic myeloid leukemia (CML) is induced by the expression of the fused tyrosine kinase BCR-ABL, which is caused by a chromosomal translocation. BCR-ABL inhibitors have been used to treat CML; however, the acquisition of resistance by CML cells during treatment
Zheng Xing et al.
The Journal of biological chemistry, 295(27), 8988-8998 (2020-05-08)
DEAD-box helicase 5 (DDX5) is a founding member of the DEAD-box RNA helicase family, a group of enzymes that regulate ribonucleoprotein formation and function in every aspect of RNA metabolism, ranging from synthesis to decay. Our laboratory previously found that

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