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Merck
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Key Documents

05-736

Sigma-Aldrich

Anti-phospho-Akt1/PKBα (Ser473) Antibody, clone SK703, rabbit monoclonal

clone SK703, Upstate®, from rabbit

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

SK703, monoclonal

Espèces réactives

human, mouse

Fabricant/nom de marque

Upstate®

Technique(s)

western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

phosphorylation (pSer473)

Informations sur le gène

human ... AKT1(207)

Spécificité

phosphorylated Akt1/PKBa

Immunogène

Peptide containing a pSer that corresponds to amino acid position 473 of human Akt1/PKBa

Application

Detect phospho-Akt1/PKBα (Ser473) using this Anti-Akt1 Antibody, clone SK703 validated for use in WB.
Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling

Qualité

routinely evaluated by immunoblot on lysates from mouse NIH-3T3 fibroblasts treated with PDGF

Description de la cible

60kDa

Forme physique

Format: Purified
Protein A purified
Protein A purified antibody in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide.

Stockage et stabilité

Stable refrigerated at 2-8°C in undiluted aliquots for up to 1 year from date of receipt.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Matthew J Nelson et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 300(4), R993-R1000 (2011-02-11)
The purpose of this study was to test the hypothesis that exercise-induced cardiac adaptations would be attenuated by the free radical scavenger N-2-mercaptopropionyl glycine (MPG). Male Sprague-Dawley rats were divided into four groups (n = 9-13 per group) for 3-4
Chenran Zhang et al.
BMC cancer, 15, 990-990 (2015-12-23)
Retinoblastoma protein-interacting zinc-finger gene 1 (RIZ1) displays strong tumor suppressive activities, and its expression is often silenced in many types of human tumors. However, the relationship between RIZ1 expression and glioma prognosis remains unclear. The dysregulation of RIZ1 was evaluated
Inducible-NOS but not neuronal-NOS participate in the acute effect of TNF-alpha on hypothalamic insulin-dependent inhibition of food intake.
Juliana C Moraes, Maria E Amaral, Paty K Picardi, Vivian C Calegari, Talita Romanatto et al.
Febs Letters null
Giorgio Zauli et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 17(4), 762-770 (2010-11-26)
To analyze the effect of the combination of Dasatinib, a multikinase inhibitor, plus Nutlin-3, a nongenotoxic activator of the p53 pathway, in primary B chronic lymphocytic leukemia (B-CLL) patient samples and B leukemic cell line models. The induction of cytotoxicity
Cereal and nonfat milk support muscle recovery following exercise.
Lynne Kammer, Zhenping Ding, Bei Wang, Daiske Hara, Yi-Hung Liao, John L Ivy et al.
Journal of the International Society of Sports Nutrition null

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