05-23-0751

α-Melanocyte-Stimulating Hormone

Synthetic α-melanocyte-stimulating hormone.

• Synonyme(s) : α-Melanocyte-Stimulating Hormone, α-MSH, Melanotropin
• Formule empirique (notation de Hill): C₇₇H₁₀₉N₂₁O₁₉S
• Numéro CAS: 581-05-5
• Poids moléculaire : 1664.88
• Numéro MDL: MFCD00133062
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Stérilité: non-sterile
• Pureté: ≥95% (HPLC)
• Forme: lyophilized
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Solubilité: water: 1 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• InChI: 1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58?,59-,60-,61-,64-/m0/s1
• Clé InChI: WHNFPRLDDSXQCL-PDEGJNOBSA-N

Description

Description générale

Synthetic α-melanocyte-stimulating hormone. Peptide hormone secreted by the anterior pituitary gland. Controls the intensity of pigmentation. A potent inhibitor of ICAM-1 expression in malignant melanocytes.

Conditionnement

Yes

Avertissement

Toxicity: Standard Handling (A)

Séquence

Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂

Forme physique

Supplied as trifluoroacetate salt. Sold on the basis of peptide content.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Autres remarques

Morandini, R., et al. 1998. J. Cell Physiol. 175, 276.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable