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Merck
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Key Documents

04-004

Sigma-Aldrich

Anti-SOCS3 Antibody, clone 1B2

clone 1B2, Upstate®, from mouse

Synonyme(s) :

suppressor of cytokine signaling 3, ATOD4, CIS3, Cish3, MGC71791, SOCS-3, SSI-3, SSI3

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

1B2, monoclonal

Espèces réactives

mouse, human

Fabricant/nom de marque

Upstate®

Technique(s)

western blot: suitable

Isotype

IgG1

Numéro d'accès NCBI

NM_003955.3

Numéro d'accès UniProt

O14543

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... SOCS3(9021)

Spécificité

Recognizes SOCS3.

Immunogène

mouse SOCS3 recombinant GST fusion protein encompassing amino acids 2-44.

Application

Research Sub Category
Neuroregenerative Medicine

Developmental Neuroscience
This Anti-SOCS3 Antibody, clone 1B2 is validated for use in WB for the detection of SOCS3.

Qualité

Routinely evaluated by immunoblot.

Description de la cible

25 kDa

Forme physique

Format: Purified
Protein G Purified mouse monoclonal IgG in a solution of 50% glycerol, 0.02 M Phosphate buffer, pH 7.6, 0.25 M NaCl, 0.1% sodium azide as a preservative.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Sam Ansari et al.
Scientific data, 3, 150077-150077 (2016-01-06)
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of an aerosol derived from a prototype
Daniel J Ham et al.
American journal of physiology. Endocrinology and metabolism, 310(11), E970-E981 (2016-04-21)
Amino acids, especially leucine, potently stimulate protein synthesis and reduce protein breakdown in healthy skeletal muscle and as a result have received considerable attention as potential treatments for muscle wasting. However, the normal anabolic response to amino acids is impaired
Kate D Sutherland et al.
Oncogene, 23(46), 7726-7733 (2004-09-14)
Suppressor of cytokine signaling (SOCS) proteins have emerged as critical attenuators of cytokine-mediated processes, suggesting a role in the suppression of tumorigenesis. In the ovary and mammary gland, cytokines such as prolactin and IL-6 are important regulators of growth and
Zhenkun Yan et al.
Cancer management and research, 13, 3029-3039 (2021-04-16)
Dysregulation of microRNAs (miRNAs), which represented a critical level of gene expression modulation, regulated the development of colorectal cancer. However, the functions of numerous miRNAs remain unclear in colorectal cancer. The microarray data of GSE115513 were retrieved; subsequently, the differentially
Evdokia Dimitriadis et al.
Endocrinology, 147(8), 3809-3817 (2006-05-20)
The differentiation of endometrial stromal cells into decidual cells (decidualization) is critical for embryo implantation, but the mechanisms remain poorly defined. Numerous paracrine agents including IL-11 promote human endometrial stromal cell (HESC) decidualization. IL-11 signaling is transduced by the signal
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