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T-068

Supelco

Tilidine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formule empirique (notation de Hill):
C17H23NO2 · HCl
Numéro CAS:
27107-79-5
Poids moléculaire :
309.83
Numéro CE :
200-659-6
Numéro MDL:
MFCD01735084
Code UNSPSC :
41116107
ID de substance PubChem :
329826611
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Niveau de qualité

300

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

Concentration

1.0 mg/mL in methanol (as free base)

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

forensics and toxicology

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

Cl.CCOC(=O)[C@@]1(CCC=C[C@H]1N(C)C)c2ccccc2

InChI

1S/C17H23NO2.ClH/c1-4-20-16(19)17(14-10-6-5-7-11-14)13-9-8-12-15(17)18(2)3;/h5-8,10-12,15H,4,9,13H2,1-3H3;1H/t15-,17+;/m1./s1

Clé InChI

MUWDJVKYGSDUSH-KALLACGZSA-N

Catégories apparentées

Description générale

Tilidine is a synthetic opioid analgesic used mainly in Germany, Switzerland and Belgium for treatment of moderate to severe pain, both acute and chronic. While tilidine is considered a moderately-potent opioid, its active metabolite nortilidine possesses analgesic effects roughly equivalent to that of morphine.

Application

  • Opioid Detection in Hair: Research demonstrated the application of liquid chromatography/tandem mass spectrometry for detecting opioids, including Tilidine, in hair samples from palliative care patients, offering insights into long-term drug use and compliance monitoring (Musshoff et al., 2007).

  • Drug Testing in Hair Analysis: An analytical technique using LC-ESI-MS/MS and MALDI-MS/MS imaging was utilized to distinguish between Tilidine intake and external contamination in segmental hair analysis, improving accuracy in drug testing scenarios (Poetzsch et al., 2015).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

Certificats d'analyse (COA)

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[The transdermal 7-day buprenorphine patch--an effective and safe treatment option, if tramadol or tilidate/naloxone is insufficient. Results of a non-interventional study].
Ulf Schutter et al.
MMW Fortschritte der Medizin, 152(31-33), 49-49 (2010-09-11)
Canli Zhang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(22), 2089-2094 (2011-06-21)
We report in this manuscript, the use of direct ammonium persulfate-enhanced chemiluminescence (CL) imaging, to monitor changes to measure serum salbutamol concentration in subjects of different haptoglobin (Hp) phenotypes at different dosing time. It was noted that CL generated from
[Chronic non-malignant pain. Opioids are also suitable for long-term treatment].
R Wörz
MMW Fortschritte der Medizin, 148(17), 47-47 (2006-05-23)
Christoph Köhler et al.
Analytical and bioanalytical chemistry, 400(1), 17-23 (2010-12-09)
The opioid tilidine is a prodrug which is hepatically metabolized to active nortilidine and bisnortilidine. Due to the increasing abuse of tilidine by drug users and the lack of a specific immunoassay, we developed an analytical method for the quantification
[The chronic pain patient: assuring long-term success].
Thomas Nolte
Krankenpflege Journal, 43(7-10), 203-203 (2006-03-07)
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