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Key Documents

P-077

Supelco

Propofol-D17 solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formule empirique (notation de Hill):
C12D17HO
Numéro CAS:
Poids moléculaire :
195.38
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Niveau de qualité

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

Concentration

100 μg/mL in methanol

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

forensics and toxicology

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

OC1=C(C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C([2H])=C([2H])C([2H])=C1C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]

InChI

1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3/i1D3,2D3,3D3,4D3,5D,6D,7D,8D,9D

Clé InChI

OLBCVFGFOZPWHH-ACWNEFEHSA-N

Description générale

Propofol, also known as Diprivan®, is a short-acting, hypnotic drug intravenously administered for the induction and maintenance of general anesthesia and sedation. This internal standard is suitable for a variety of uses including forensic and forensic toxicology analysis, isotope dilution methods, calibrator preparation, and drug monitoring in plasma or whole blood.

Application


  • Propofol-D₁₇ in forensic analysis: Propofol-D₁₇ was utilized to confirm testimonial evidence in serial homicide cases through drug detection in decomposed cadavers, demonstrating its value in complex forensic scenarios (Ottaviano et al., 2021).

  • Pharmacokinetic studies with Propofol-D₁₇: A sensitive LC-APCI-MS/MS method was developed using Propofol-D₁₇ to quantify propofol in a bioequivalence study among healthy Chinese subjects, enhancing understanding of its pharmacokinetics (Tang et al., 2020).

  • Evaluation of analytical methods using Propofol-D₁₇: Comparative analysis of LC-MS/MS and GC-MS for propofol detection highlights Propofol-D₁₇′s role in improving analytical procedures for forensic and clinical toxicology (Vaiano et al., 2015).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Diprivan is a registered trademark of Abraxis Bioscience, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

FlameSkull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup


Certificats d'analyse (COA)

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