860501P
Avanti
C22 Ceramide (d18:1/22:0)
Avanti Research™ - A Croda Brand 860501P, powder
Synonyme(s) :
N-behenoyl-D-erythro-sphingosine
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About This Item
Formule empirique (notation de Hill):
C40H79NO3
Numéro CAS:
Poids moléculaire :
622.06
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25
Produits recommandés
Forme
powder
Conditionnement
pkg of 1 × 10 mg (860501P-10mg)
pkg of 1 × 5 mg (860501P-5mg)
Fabricant/nom de marque
Avanti Research™ - A Croda Brand 860501P
Type de lipide
sphingolipids
Conditions d'expédition
dry ice
Température de stockage
−20°C
Chaîne SMILES
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
Description générale
C22 Ceramide (d18:1/22:0) or N-behenoyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with behenic acid.
Application
C22 Ceramide (d18:1/22:0) has been used:
- as a standard to measure ceramide concentrations in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2)
- as a standard for the quantitation of sphingolipid metabolites
- to study its effects on mitochondrial-to-cytosolic stress response (MCSR) induction
Actions biochimiques/physiologiques
Ceramides plays an important role in regulating cell differentiation, proliferation and apoptosis. It also regulates stress responses and inflammation.
Conditionnement
5 mL Amber Glass Screw Cap Vial (860501P-10mg)
5 mL Amber Glass Screw Cap Vial (860501P-5mg)
Informations légales
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Souvent commandé avec ce produit
Code de la classe de stockage
11 - Combustible Solids
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Les clients ont également consulté
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Mutay Aslan et al.
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Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Ebru Afşar et al.
Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor
Xingzhong Zhang et al.
Cell metabolism, 30(5), 937-951 (2019-11-02)
Obesity-induced adipose dysfunction is a major contributor to atherosclerosis. Cold exposure has been reported to affect atherosclerosis through regulation of adipose function, but the mechanism has not been well clarified. Here, adipocyte hypoxia-inducible factor 2α (HIF-2α) was upregulated after mild cold
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