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850445C

Avanti

14:0-16:0 PC

1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine, chloroform

Synonyme(s) :

1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; MPPC; PC(14:0/16:0)

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About This Item

Formule empirique (notation de Hill):
C38H76NO8P
Numéro CAS:
69525-80-0
Poids moléculaire :
705.99
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

liquid

Conditionnement

pkg of 1 × 2.5 mL (850445C-25mg)
pkg of 1 × 20 mL (850445C-500mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 850445C

Concentration

10 mg/mL (850445C-25mg)
25 mg/mL (850445C-500mg)

Type de lipide

cardiolipins
phospholipids

Conditions d'expédition

dry ice

Température de stockage

−20°C

InChI

1S/C38H76NO8P/c1-6-8-10-12-14-16-18-19-21-23-25-27-29-31-38(41)47-36(35-46-48(42,43)45-33-32-39(3,4)5)34-44-37(40)30-28-26-24-22-20-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/t36-/m1/s1

Clé InChI

RFVFQQWKPSOBED-PSXMRANNSA-N

Description générale

Phosphatidylcholine (PC) is dietary source of choline. 14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) is a water-soluble lysolipid. 14:0-16:0 PC is a symmetrical phosphatidylcholine.

Application

14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) has been used to generate Wnt3a liposomes. It has also been used as a calibration standard for lipidomic analysis by liquid chromatography–tandem mass spectrometry (LC-MS). It may be used in the bilayer membrane to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC).

Actions biochimiques/physiologiques

Phosphatidylcholine (PC) is involved in the fusion and transport of membranes. It is known to play a vital role in endocytosis and the catalytic activity of enzymes.

Conditionnement

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850445C-500mg)
5 mL Clear Glass Sealed Ampule (850445C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Organes cibles

Liver,Kidney, Respiratory system

Code de la classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

does not flash

Point d'éclair (°C)

does not flash

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

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Jeffrey K Mills et al.
Biochimica et biophysica acta, 1716(2), 77-96 (2005-10-12)
The enhanced permeability of lipid bilayer membranes at their gel-to-liquid phase transition has been explained using a "bilayer lipid heterogeneity" model, postulating leaky interfacial regions between still solid and melting liquid phases. The addition of lysolipid to dipalmitoylphosphatidylcholine bilayers dramatically
Bohdana Térová et al.
Biochimica et biophysica acta, 1667(2), 182-189 (2004-12-08)
In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs
Li-Juan Zhao et al.
Journal of ethnopharmacology, 260, 112943-112943 (2020-05-19)
Arenobufagin (ArBu) is an important anti-tumor ingredient of Chan'su which has long been used as traditional Chinese medicine in clinic for tumor therapy in China. The purpose of our study is to investigate the lipid homeostasis regulation effects of ArBu
Ségolène Hescot et al.
Oncotarget, 8(66), 109924-109940 (2018-01-05)
Mitotane (o,p'DDD), the most effective drug in adrenocortical carcinoma, concentrates into the mitochondria and impacts mitochondrial functions. To address the molecular mechanisms of mitotane action and to identify its potential target, metabolomic and lipidomic approaches as well as imaging analyses
Dana K Shaw et al.
Nature communications, 8, 14401-14401 (2017-02-15)
The insect immune deficiency (IMD) pathway resembles the tumour necrosis factor receptor network in mammals and senses diaminopimelic-type peptidoglycans present in Gram-negative bacteria. Whether unidentified chemical moieties activate the IMD signalling cascade remains unknown. Here, we show that infection-derived lipids
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