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850399P

Avanti

24:1 (Cis) PC

1,2-dinervonoyl-sn-glycero-3-phosphocholine, powder

Synonyme(s) :

1,2-di-(15Z-tetracosenoyl)-sn-glycero-3-phosphocholine; PC(24:1(15Z)/24:1(15Z)); 110930

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About This Item

Formule empirique (notation de Hill):
C56H108NO8P
Numéro CAS:
51779-96-5
Poids moléculaire :
954.43
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 25 mg (850399P-25mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 850399P

Type de lipide

cardiolipins
phospholipids

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)=O

InChI

1S/C56H108NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-46-48-55(58)62-52-54(53-64-66(60,61)63-51-50-57(3,4)5)65-56(59)49-47-45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,54H,6-19,24-53H2,1-5H3/b22-20-,23-21-/t54-/m1/s1

Clé InChI

REWNAIYQZZOESC-CGKZWXATSA-N

Description générale

24:1 (Cis) PC (1,2-dinervonoyl-sn-glycero-3-phosphocholine) has two 24 carbon fatty acid chains, each having one cis double bond at the 15th carbon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

24:1 (Cis) PC (1,2-dinervonoyl-sn-glycero-3-phosphocholine) may be used in planar bilayer lipid membranes (BLMs) to study the effect of lipid chain length on single-channel properties of C-terminal colicin peptide (P178). It may also be used in planar bilayers to explore the single channel activities of BKCa (hSlo α-subunit) channels.

Actions biochimiques/physiologiques

Phosphatidylcholine (PC) may participate in the signaling of neuronal differentiation.

Conditionnement

5 mL Clear Glass Sealed Ampule (850399P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Chunbo Yuan et al.
The Journal of biological chemistry, 282(10), 7276-7286 (2007-01-09)
Transmembrane segments of ion channels tend to match the hydrophobic thickness of lipid bilayers to minimize mismatch energy and to maintain their proper organization and function. To probe how ion channels respond to mismatch with lipid bilayers of different thicknesses
Alexander A Sobko et al.
The Journal of biological chemistry, 281(20), 14408-14416 (2006-03-25)
Colicin E1 belongs to a group of bacteriocins whose cytotoxicity toward Escherichia coli is exerted through formation of ion channels that depolarize the cytoplasmic membrane. The lipid dependence of colicin single-channel conductance demonstrated intimate involvement of lipid in the structure
Luciana Paoletti et al.
IUBMB life, 63(9), 714-720 (2011-08-06)
Neuronal differentiation is characterized by neuritogenesis and neurite outgrowth, processes, which are critically dependent on membrane biosynthesis, and therefore, on the expression and regulation of enzymes involved in phospholipid biosynthesis. During the last decade a great effort was made to

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