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840034P

Avanti

16:0-18:1 PS (POPS)

Avanti Research - A Croda Brand

Synonyme(s) :

1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); POPS; PS(16:0/18:1(9Z)); 110669

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About This Item

Formule empirique (notation de Hill):
C40H75NO10PNa
Numéro CAS:
Poids moléculaire :
783.99
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Description

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt)

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 10 mg (840034P-10mg)
pkg of 2 × 100 mg (840034P-200mg)
pkg of 5 × 100 mg (840034P-500mg)
pkg of 1 × 25 mg (840034P-25mg)

Fabricant/nom de marque

Avanti Research - A Croda Brand

Type de lipide

phospholipids
cardiolipins

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

Description générale

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.

Application

16:0-18:1 PS (POPS) has been used:
  • in phospholipid mixture for nanodisc preparation
  • in liposome preparation
  • in lipid vesicle preparation for surface plasmon resonance (SPR) analysis

Actions biochimiques/physiologiques

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It has the ability to cross the blood-brain barrier. It plays a key role in the formation of short-term memory, the ability to create new memories, to focus attention, to reason and solve problems and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.

Conditionnement

5 mL Clear Glass Sealed Ampule (840034P-10mg)
5 mL Clear Glass Sealed Ampule (840034P-200mg)
5 mL Clear Glass Sealed Ampule (840034P-25mg)
5 mL Clear Glass Sealed Ampule (840034P-500mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Fluorophore Labeling, Nanodisc Reconstitution and Single-molecule Observation of a G Protein-coupled Receptor
Lamichhane R, et al.
Bio-protocol, 7(12) (2017)
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Journal of chemical theory and computation, 16(1), 738-748 (2019-11-26)
Phosphatidylserine (PS) lipids are important signaling molecules and the most common negatively charged lipids in eukaryotic membranes. The signaling can be often regulated by calcium, but its interactions with PS headgroups are not fully understood. Classical molecular dynamics (MD) simulations
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Phosphatidylserine (PS) has previously been found to bind Cu2+ in a ratio of 1 Cu2+ ion per 2 PS lipids to form a complex with an apparent dissociation constant that can be as low as picomolar. While the affinity of

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