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Merck
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Key Documents

T16403

Sigma-Aldrich

2,2′,4,4′-Tetrahydroxybenzophenone

97%

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About This Item

Formule linéaire :
[(HO)2C6H3]2CO
Numéro CAS:
Poids moléculaire :
246.22
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22

Niveau de qualité

Pureté

97%

Pf

198-200 °C (lit.)

Chaîne SMILES 

Oc1ccc(c(O)c1)C(=O)c2ccc(O)cc2O

InChI

1S/C13H10O5/c14-7-1-3-9(11(16)5-7)13(18)10-4-2-8(15)6-12(10)17/h1-6,14-17H

Clé InChI

WXNRYSGJLQFHBR-UHFFFAOYSA-N

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Application


  • Urinary concentrations of bisphenol A, parabens and benzophenone-type ultra violet light filters in relation to sperm DNA fragmentation in young men: A chemical mixtures approach.: This study investigates the relationship between urinary concentrations of various chemicals, including benzophenone-type UV filters like 2,2′,4,4′-Tetrahydroxybenzophenone, and sperm DNA fragmentation. The findings highlight potential reproductive toxicity risks associated with exposure to these compounds (Kiwitt-Cárdenas et al., 2024).

  • Salting-out assisted liquid-liquid extraction combined with LC-MS/MS for the simultaneous determination of seven organic UV filters in environmental water samples: method development and application.: This paper discusses the development of a method for detecting organic UV filters, including 2,2′,4,4′-Tetrahydroxybenzophenone, in environmental water samples. The method offers a reliable way to monitor the presence of these compounds in the environment (Carve et al., 2023).

  • Novel visible-light-active P-g-CN-based α-Bi(2)O(3)/WO(3) ternary photocatalysts with a dual Z-scheme heterostructure for the efficient decomposition of refractory ultraviolet filters and environmental hormones: Benzophenones.: The study presents a new photocatalyst capable of degrading benzophenone-type UV filters, including 2,2′,4,4′-Tetrahydroxybenzophenone, under visible light. This development has significant implications for environmental cleanup technologies (Berekute et al., 2023).

  • Boosting elimination of sunscreen, Tetrahydroxybenzophenone (BP-2), from water using monopersulfate activated by thorny NanoBox of Co@C prepared via the engineered etching strategy: A comparative and mechanistic investigation.: This research explores a novel method for removing 2,2′,4,4′-Tetrahydroxybenzophenone from water using advanced nanotechnology, highlighting its effectiveness and potential for environmental applications (Khiem et al., 2023).

  • The binding mechanism of benzophenone-type UV filters and human serum albumin: The role of site, number, and type of functional group substitutions.: The study examines how benzophenone-type UV filters, including 2,2′,4,4′-Tetrahydroxybenzophenone, interact with human serum albumin, providing insights into their behavior in biological systems and potential health implications (Ma et al., 2023).

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1A

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


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Les clients ont également consulté

Hubertus Jarry et al.
Toxicology, 205(1-2), 87-93 (2004-10-02)
The chemical industry has developed sun protection factor products, which contain a variety of so-called "UV screens", among others, benzophenones (BP). Based on the structure it can be assumed, that the variant BP2 may be a potent estrogenic endocrine disrupter
Armin Zenker et al.
Journal of chromatography. A, 1202(1), 64-74 (2008-07-18)
A new sensitive method has been successfully developed and validated for the simultaneous determination and quantification of nine estrogenic UV filters (benzophenone-1, benzophenone-2, benzophenone-3, benzophenone-4, 4,4-dihydroxybenzophenone, ethyl-4-aminobenzoate, 2-ethyl-hexyl-4-trimethoxycinnamate, 3-(4-methylbenzylidene)-camphor, 3-benzylidene-camphor) in different environmental matrices. After optimisation of extraction conditions for
Christin J Weisbrod et al.
Toxicology and applied pharmacology, 225(3), 255-266 (2007-09-25)
The UV filter benzophenone-2 (BP-2) is largely used in personal care products such as cosmetics and in numerous other materials for UV protection. Like other UV filters, BP-2 has been found to be estrogenic in vitro and in vivo, but
Dana Seidlová-Wuttke et al.
Toxicology, 213(1-2), 13-24 (2005-06-14)
The endocrine active substances BPA, DBP and BP2 have estrogenic effects in the uterus. Proc and Lin were shown to be antiandrogenic. Whether other estrogen-regulated parameters like lipids, fat metabolism and hormones are also affected by these substances is unknown.
Michael H Hsieh et al.
The Journal of urology, 178(4 Pt 2), 1637-1642 (2007-08-21)
Additives such as benzophenone-2 are commonly used in cosmetic products and food container plastics to filter out ultraviolet light. In pregnant women exposure may result in transplacental transfer of benzophenone-2 to fetuses. Benzophenone-2 is estrogenic in vitro and in the

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