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C85778

Sigma-Aldrich

o-Cresolphthalein

Indicator grade, powder

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About This Item

Formule empirique (notation de Hill):
C22H18O4
Numéro CAS:
596-27-0
Poids moléculaire :
346.38
Numéro Beilstein :
310554
Numéro CE :
209-881-8
Numéro MDL:
MFCD00005912
Code UNSPSC :
12171500
ID de substance PubChem :
24893078
Nomenclature NACRES :
NA.47

product name

o-Cresolphthalein, indicator grade

Qualité

indicator grade

Niveau de qualité

200

Forme

powder

Technique(s)

titration: suitable

Couleur

beige

pH

8.2-9.8, colorless to red

Pf

219-221 °C (lit.)

λmax

381 nm (2nd)
566 nm

ε (coefficient d'extinction)

≥10000 at 294-300 nm
≥39000 at 564-570 nm
≥5000 at 378-384 nm

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

Chaîne SMILES 

Cc1cc(ccc1O)C2(OC(=O)c3ccccc23)c4ccc(O)c(C)c4

InChI

1S/C22H18O4/c1-13-11-15(7-9-19(13)23)22(16-8-10-20(24)14(2)12-16)18-6-4-3-5-17(18)21(25)26-22/h3-12,23-24H,1-2H3

Clé InChI

CPBJMKMKNCRKQB-UHFFFAOYSA-N

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Application

O-Cresolphthalein has been used as a component in calcifying media for calcification assay.

Actions biochimiques/physiologiques

o-Cresolphthalein is a reversible pH indicator. The kinetics of the reverse pathway (red-purple to colorless) is slow, thereby making it an appropriate molecule to check flow patterns in ducts with corrugated walls. It is also used for the colorimetric determination of calcium content via the o-cresolphthalein complexone method. Binding of calcium to o-cresolphthalein, in the presence of alkaline conditions (pH 10-12), results in the formation of a red complex with an absorbance at 570-575nm.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
SHBR5596
SHBR0493
MKCK2964
MKCG9431
MKCF7134

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Jin-Hyun Kim et al.
PloS one, 14(4), e0215244-e0215244 (2019-04-17)
In the stratum corneum, the intercellular junction made up of cadherin proteins provides the structural integrity of the framework. Ca2+ ions are known to play a key role in maintaining this junction. In this study, we hypothesized that Ca2+ chelation
Hyunseok Peter Kang et al.
Clinical chemistry, 50(4), 741-746 (2004-02-14)
Gadolinium formulations, which are administered as contrast agents in magnetic resonance imaging examinations, interfere with colorimetric serum calcium determinations. We performed an in vitro study to determine the extent to which three gadolinium formulations-gadodiamide (Omniscan), gadopentetate dimeglumine (Magnevist), and gadoversetamide
Natalia Campos-Obando et al.
European journal of epidemiology (2018-05-17)
Hyperphosphatemia has been associated with increased mortality in chronic kidney disease but the nature of such a relation in the general population is unclear. To investigate the association between phosphate (P) levels and all-cause and cause-specific mortality, we assessed two
P Sótonyi et al.
Histochemistry, 75(3), 425-436 (1982-01-01)
The ortho-cresolphtalein complex was successfully adapted for the electron microscopic cytochemical demonstration of calcium. The reaction product is of granular nature with sufficient electron density for finer localization. Intense precipitation was found on the sarcolemma and transverse tubules and in
Ali Duran et al.
Journal of hazardous materials, 169(1-3), 466-471 (2009-04-29)
In present study preconcentration followed by solid phase extraction of heavy metal ions, Cu(II), Co(II), Ni(II) and Pb(II) using a multiwalled carbon nanotubes (MWNTs) and complexing reagent o-cresolphthalein complexone were investigated. The effects of parameters, including pH of the solutions
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