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Merck
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Key Documents

935425

Sigma-Aldrich

Gelatin from cold water fish skin

low endotoxin

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About This Item

Code UNSPSC :
51241857
Nomenclature NACRES :
NA.21

Niveau de qualité

100

Forme

powder (chunks or fibers)

Impuretés

<10 CFU/g Bioburden (fungal)
<10 CFU/g Bioburden (total aerobic)
125 EU/g Endotoxin

Couleur

white to pale yellow

Température de stockage

2-8°C

Description générale

Gelatin is widely used for tissue engineering and 3D Bioprinting applications. Gelatin is derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications. While gelatin from porcine skin is known for its thermoreversible gelling properties, Gelatin from cold water fish skin has low gelling and melting points. This gelatin will not gel at 10°C, hence they do not have bloom strength. This unique gelatin property makes this an attractive biomaterial which are hindered by the higher thermogelation property of porcine skin such as vat-polymerization based bioprinting and microfluidics.

Application

  • Hydrogels
  • Tissue engineering
  • Bioprinting
  • Drug delivery system

Caractéristiques et avantages

  • Naturally derived polymer
  • Low gelling and melting points
  • Thermoreversible gelling properties
  • Low endotoxin and low bioburden
Low Endotoxin, low bioburden: Endotoxins have been demonstrated negatively impact cellular growth, morphology, differentiation, inflammation and protein expression. Bioburden is defined as the number of contaminated organisms found in a given amount of material. We test each lot for endotoxins as well as total bioburden (aerobic and fungal) to minimize unwanted interactions. For more information visit: Cell Culture FAQs: Bacterial Endotoxin Contamination

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Hee Jeong Yoon et al.
PloS one, 11(10), e0163902-e0163902 (2016-10-11)
Gelatin methacryloyl (GelMA) is a versatile biomaterial that has been used in various biomedical fields. Thus far, however, GelMA is mostly obtained from mammalian sources, which are associated with a risk of transmission of diseases, such as mad cow disease
Svetlana R Derkach et al.
Polymers, 12(12), 3051-3051 (2020-12-24)
This review considers the main properties of fish gelatin that determine its use in food technologies. A comparative analysis of the amino acid composition of gelatin from cold-water and warm-water fish species, in comparison with gelatin from mammals, which is
Abudureheman Maihemuti et al.
Bioactive materials, 26, 77-87 (2023-03-07)
Knee osteoarthritis is a chronic disease caused by the deterioration of the knee joint due to various factors such as aging, trauma, and obesity, and the nonrenewable nature of the injured cartilage makes the treatment of osteoarthritis challenging. Here, we
Svetlana R Derkach et al.
Polymers, 13(5), 743-743 (2021-03-07)
Polyelectrolyte complexes of sodium alginate and gelatin obtained from cold-blooded fish were studied for potential application as structure-forming agents in food hydrogels. The mass ratio of sodium alginate to gelatin plays a decisive role in the sol-gel transition and rheological

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