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Key Documents

923745

Sigma-Aldrich

INVIVO-GEL BMP2 bioink

suitable for 3D bioprinting applications

Synonyme(s) :

3D bioprinting, 3DBP, ECM

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About This Item

Code UNSPSC :
12352201
Nomenclature NACRES :
NA.23

Niveau de qualité

Température de stockage

2-8°C

Application

INVIVO-GEL BMP2 bioink is specifically developed and optimized for 3D bioprinting applications. The INVIVO-GEL BMP2 bioink kit includes optimally formulated BMP-2 mimetic peptide conjugated gelatin-based hydrogel complex packed in syringe for easy dispensing. The kit also includes Gel-linker, which reinforces mechanical stability. A transparent hydrogel forms when contents are properly mixed and exposed to UV light. This bioink is capable of generating mechanically stable 3D structures that can be maintained for days in the culture environment. BMP-2 is a potent osteoinductive growth that belongs to the transforming growth factor-â (TGF-â) protein superfamily. BMP-2 stimulates MSCs towards osteogenic differentiation, and significantly increased bone formation.

Composants

INVIVO-GEL BMP2 in syringe 5mL x 2

Gel-linker(A) powder 500µL x 1

Gel-linker(B) powder 1µL x 1

Pictogrammes

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Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Sens. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3


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Gelatin methacryloyl and its hydrogels with an exceptional degree of controllability and batch-to-batch consistency
Zhu et al.
Scientific Reports, 9 (2019)
Michelle T Poldervaart et al.
PloS one, 8(8), e72610-e72610 (2013-08-27)
The design of bioactive three-dimensional (3D) scaffolds is a major focus in bone tissue engineering. Incorporation of growth factors into bioprinted scaffolds offers many new possibilities regarding both biological and architectural properties of the scaffolds. This study investigates whether the
Shining Xiao et al.
Stem cell reviews and reports, 15(5), 664-679 (2019-06-04)
Gelatin methacrylate (GelMA)-based hydrogels are gaining a great deal of attention as potentially implantable materials in tissue engineering applications because of their biofunctionality and mechanical tenability. Since different natural tissues respond differently to mechanical stresses, an ideal implanted material would
Mengxiang Zhu et al.
Scientific reports, 9(1), 6863-6863 (2019-05-06)
Gelatin methacryloyl (GelMA) is a versatile material for a wide range of bioapplications. There is an intense interest in developing effective chemical strategies to prepare GelMA with a high degree of batch-to-batch consistency and controllability in terms of methacryloyl functionalization
Kan Yue et al.
Biomaterials, 73, 254-271 (2015-09-29)
Gelatin methacryloyl (GelMA) hydrogels have been widely used for various biomedical applications due to their suitable biological properties and tunable physical characteristics. GelMA hydrogels closely resemble some essential properties of native extracellular matrix (ECM) due to the presence of cell-attaching

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