803464

BS(PEG)9

• Synonyme(s) : 1,31-Bis(2,5-dioxo-1-pyrrolidinyl) 4,7,10,13,16,19,22,25,28-nonaoxahentriacontanedioate
• Formule empirique (notation de Hill): C₃₀H₄₈N₂O₁₇
• Numéro CAS: 1008402-79-6
• Poids moléculaire : 708.71
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.22

Propriétés

• Forme: oil
• Niveau de qualité: 100
• Poids mol.: 708.71
• Pertinence de la réaction: reagent type: cross-linking reagent
• Conditions de stockage: desiccated
• Solubilité: water: soluble
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

By contrast to typical PEG reagents that contain heterogeneous mixtures of different PEG chain lengths, this PEG reagent is a homogeneous compound of defined molecular weight and spacer arm length, providing greater precision in optimization and characterization of crosslinking applications.

Application

BS(PEG)9 can be used as a cross-linker

• To study the domain structure of BfmR, a regulator of biofilm formation in Acinetobacter baumannii.
• In the study of the mechanism of visual excitation.

Caractéristiques et avantages

• Reactive groups: sulfo-NHS ester (both ends)
• Reactive towards: amino groups (primary amines)
• NHS esters react with—NH2 groups at pH 7-9, forming stable amide bonds
• Water-soluble; compare to non-pegylated BS3 (also soluble) and DSS (water-insoluble)
• Membrane-impermeable, allowing for cell surface labeling
• Irreversibly crosslink proteins or peptides by flexible PEG spacer arms
• Polyethylene glycol spacer arms help maintain conjugate solubility
• Pure compound with defined structure and molecular weight, ensuring reproducible protein-modification effects
• PEG spacer provides unique advantages, including increased stability, reduced tendency toward aggregation and reduced immunogenicity
• Ideal for small molecule or peptide conjugations

Attention

This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable