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793248

Sigma-Aldrich

Polyhydroxylated fullerenes, water soluble

Synonyme(s) :

C60(OH)n, water soluble C60, Fullerenols, Polyhydroxy fullerenes

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About This Item

Formule empirique (notation de Hill):
C60(OH)n · mH2O (n>40, m>8)
Code UNSPSC :
12352103
Nomenclature NACRES :
NA.23

Forme

solid

Niveau de qualité

Couleur

light yellow to yellow

Solubilité

water: soluble >50 mg/mL
DMSO: slightly soluble
methanol: slightly soluble

Température de stockage

2-8°C

Description générale

Polyhydroxylated fullerenes, (water soluble)(PHF) is a functionalized fullerene that is also called fullerenol which can be used as a molecular anti-oxidant and a nanoparticle. It is a non-toxic fullerene which is attached with 12-42 hydroxyl groups per molecule that result in water solubility. Its structure and the position of the hydroxyl groups will depend on the existing pH of the media.

Application

PHF may be incorporated in titanium dioxide to form a nanocomposite which can be potentially used in the photocatalysis of semiconductors. Its photothermal and therapeutic properties may be used in non-invasive image based therapy of cancer.

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Les clients ont également consulté

Facile and scalable synthesis of a highly hydroxylated water-soluble fullerenol as a single nanoparticle
Kokubo K, et al.
Nano Research, 4(2), 204-215 (2011)
Yasukazu Saitoh et al.
Journal of photochemistry and photobiology. B, Biology, 102(1), 69-76 (2010-10-15)
Polyhydroxylated fullerenes (fullerenols: C(60)(OH)(n)) are known as the major water-soluble fullerene derivatives which possess particular significance as free radical scavengers or antioxidants in biological systems. Recently, the novel polyhydroxylated fullerene (C(60) (OH)(44)·8H(2)O: SHH-F) was successfully synthesized. In the present study
Yunxiang Sun et al.
Nanoscale, 11(24), 11933-11945 (2019-06-13)
Featuring small sizes, caged structures, low cytotoxicity and the capability to cross biological barriers, fullerene hydroxy derivatives named fullerenols have been explored as nanomedicinal candidates for amyloid inhibition. Understanding the surface chemistry effect of hydroxylation extents and the corresponding amyloid
Synthesis and Biological Activity of Fullerenols with Various Contents of Hydroxyl Groups
Eropkin YM, et al.
Pharmaceutical Chemistry Journal, 47(2), 87-91 (2013)
Enhancement of nano titanium dioxide photocatalysis in transparent coatings by polyhydroxy fullerene.
Bai W, et al.
Applied Catalysis. B, Environmental, 125(1), 128-135 (2012)

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