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741884

Sigma-Aldrich

Poly(2-ethyl-2-oxazoline)

average Mn 20,000, PDI <1.4

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About This Item

Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23

Forme

solid

Niveau de qualité

100

Poids mol.

average Mn 20,000

Pf

>300 °C

PDI

<1.4

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Application

This Poly(2-ethyl-2-oxazoline) polymer is amorphous and water soluble with good temperature stability. Jordan and coworkers showed biocompatibility, no accumulation in tissue, and rapid clearance from the bloodstream1. End-group modified poly(2-ethyl-2-oxazoline)s have been conjugated to peptides2, and were shown as versatile alternatives to poly(ethylene glycol) (PEG) for both protein and small drug conjugation3.

Potential substitute for poly(vinyl alcohol) and poly(vinyl pyrrolidone). Sometimes it is used as an adhesion promoter in coatings. This is also sometimes used in heat sealing and remoistenable hot-melt adhesives. N-propionyl substituted linear polyethylenimine

Caractéristiques et avantages

Nonionic, water-soluble thermoplastic. Better heat stability than poly(vinyl alcohol). Good melt flow, shear stability and Newtonian characteristics. Water is a room temperature Theta solvent.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
MKCM9423
MKCT4282
MKCN6793
MKCN0937
MKCJ0488

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Polyéthylèneimine, ramifiée average Mw ~25,000 by LS, average Mn ~10,000 by GPC, branched

Sigma-Aldrich

408727

Polyéthylèneimine, ramifiée

Polyethylenimine, linear average Mn 2100, PDI &lt;1.3

Sigma-Aldrich

764604

Polyethylenimine, linear

Polyethylenimine, linear average Mn 5,000, PDI &#8804;1.3

Sigma-Aldrich

764582

Polyethylenimine, linear

F. C. Gaertner, R. Luxenhofer, B. Blechert, R. Jordan, M. Essler
J. Controlled Release, 119, 291-300 (2007)
R. Luxenhofer, M. Lopez-Garcia, A. Frank, H. Kessler, R. Jordan
Polym. Mater. Sci. Eng., 95, 283-284 (2006)
A. Mero, G. Pasut, L. D. Via, M.W. M. Fijten, et al.
J. Controlled Release, 125, 87-95 (2008)
Yung-Chu Chen et al.
Journal of biomedical materials research. Part A, 100(5), 1279-1292 (2012-03-01)
The multifunctional nanoparticles constructed from triphenylamine-poly(lactide-co-glycolide)-poly(ethyleneglycol)-poly(lactide-co-glycolide) (TPA-PEP) and folate-poly(2-ethyl-2oxazoline)-poly(D,L-lactide) (folate-PEOz-PLA) were developed in this study. Iron oxide nanoparticles (IOP) and paclitaxel (PTX) were coencapsulated in the nanoparticles with diameter less than 200 nm. The drug-loaded nanoparticles emit fluorescence peak at
Issa Katime et al.
Applied spectroscopy, 57(7), 829-834 (2003-12-09)
This paper reports an FT-IR study of blends of poly(mono-n-alkyl itaconates) with poly(N,N-dimethylacrylamide) (PDMA) and poly(ethyloxazoline) (PEOX). Strong hydrogen bonding has been found, and both polybases have shown similar acceptor strengths. Derivative techniques show asymmetric profiles for the free carbonyl
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Articles

Poly(2-oxazoline)s (POx) in Biomedical Applications

Poly(2-oxazoline)s, synthesized via LCROP, resemble polypeptides and have various applications in polymer chemistry.

Poly(2-oxazoline)s (POx) in Biomedical Applications

Poly(2-oxazoline)s, synthesized via LCROP, resemble polypeptides and have various applications in polymer chemistry.

Poly(2-oxazoline)s (POx) in Biomedical Applications

Poly(2-oxazoline)s, synthesized via LCROP, resemble polypeptides and have various applications in polymer chemistry.

Poly(2-oxazoline)s (POx) in Biomedical Applications

Poly(2-oxazoline)s, synthesized via LCROP, resemble polypeptides and have various applications in polymer chemistry.

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