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Merck
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Key Documents

711624

Sigma-Aldrich

1,3-Diiodo-5,5-dimethylhydantoin

≥96%

Synonyme(s) :

DIH

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About This Item

Formule empirique (notation de Hill):
C5H6I2N2O2
Numéro CAS:
Poids moléculaire :
379.92
Numéro Beilstein :
146040
Numéro MDL:
Code UNSPSC :
12352101
ID de substance PubChem :
Nomenclature NACRES :
NA.22

Niveau de qualité

Pureté

≥96%

Forme

powder

Température de stockage

−20°C

Chaîne SMILES 

CC1(C)N(I)C(=O)N(I)C1=O

InChI

1S/C5H6I2N2O2/c1-5(2)3(10)8(6)4(11)9(5)7/h1-2H3

Clé InChI

RDZHCKRAHUPIFK-UHFFFAOYSA-N

Application

DIH - Highly efficient and economical reagent for Iodination

Used for:
  • Preparation of nitriles from corresponding alcohols and amines via oxidative conversion
  • Chemoselective, stereospecific iododesilylation of silylated alkenes
  • Preparation of N-benzyl toluenesulfonamides via sulfonylamidation of alkylbenzenes with toluenesulfonamide in presence of diiododimethylhydantoin
  • Iodination reactions

Pictogrammes

Flame over circleCorrosionEnvironment

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Aquatic Acute 1 - Ox. Sol. 2 - Skin Corr. 1B

Code de la classe de stockage

5.1B - Oxidizing hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Consulter la Bibliothèque de documents

Miguel Perez-Aso et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(1), 457-465 (2015-09-30)
Ionizing radiation is a common therapeutic modality and following irradiation dermal changes, including fibrosis and atrophy, may lead to permanent changes. We have previously demonstrated that occupancy of A2A receptor (A2AR) stimulates collagen production, so we determined whether blockade or
Rui Sun et al.
Psychophysiology, 58(2), e13731-e13731 (2020-12-08)
Neurophysiological investigation of neural processes are hindered by the presence of large artifacts associated with eye movement. Although blind source separation (BSS)-based hybrid algorithms are useful for separating, identifying, and removing these artifacts from EEG, it remains unexamined to what
Yani Zhao et al.
PloS one, 6(12), e29624-e29624 (2012-01-05)
The Duffy antigen receptor for chemokines (DARC) shows high affinity binding to multiple inflammatory CC and CXC chemokines and is expressed by erythrocytes and endothelial cells. Recent evidence suggests that endothelial DARC facilitates chemokine transcytosis to promote neutrophil recruitment. However
Pamela M Vacek et al.
Occupational and environmental medicine, 74(3), 211-217 (2016-11-09)
To understand why 2 studies relating crystalline silica exposure to lung-cancer mortality in Vermont granite workers yielded conflicting results. Data used in the 2 studies were linked to identify discrepancies. Mortality data and employment histories from the earlier study were
Sukumar Namineni et al.
Journal of hepatology, 72(5), 960-975 (2020-01-19)
Hepatic innate immune control of viral infections has largely been attributed to Kupffer cells, the liver-resident macrophages. However, hepatocytes, the parenchymal cells of the liver, also possess potent immunological functions in addition to their known metabolic functions. Owing to their

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