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535311

Sigma-Aldrich

Poly(N-isopropylacrylamide)

Mn ~40,000

Synonyme(s) :

NIPAM polymer, PNIPAM, Polyacrylamide, polyNIPAM

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About This Item

Formule linéaire :
CH3(C6H11NO)nCH3
Numéro CAS:
25189-55-3
Numéro MDL:
MFCD00284282
Code UNSPSC :
12162002
ID de substance PubChem :
24877546
Nomenclature NACRES :
NA.23

Poids mol.

Mn 20,000-60,000
Mn ~40,000

Niveau de qualité

100

Pf

96 °C

Chaîne SMILES 

CC(C)NC(=O)C=C

InChI

1S/C6H11NO/c1-3-5-7-6(8)4-2/h4H,2-3,5H2,1H3,(H,7,8)

Clé InChI

WDFKEEALECCKTJ-UHFFFAOYSA-N

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Application

PNIPAM-based Smart Surfaces for Cell Sheet Tissue Engineering
Thermosensitive polymer, can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.

Forme physique

Thermosensitive polymer, hydrogel

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
MKCV7874
MKCR8778
MKCR4152
MKCM8563
MKCM8561

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Poly(N-isopropyl acrylamide) NHS ester end functionalized, average Mn 5,000

Sigma-Aldrich

900188

Poly(N-isopropyl acrylamide)

N-Isopropylmethacrylamide 97%

Sigma-Aldrich

423548

N-Isopropylmethacrylamide

Soichi Takagi et al.
Cell transplantation, 21(2-3), 411-420 (2012-07-17)
The de novo engineering of a uniform hepatocyte sheet in vitro is considered as a novel approach for liver-directed therapeutics. Hepatocytes can be cultured on a temperature-responsive culture dishes coated with poly(N-isopropylacrylamide) (PIPAAm). Following multiple days of culturing, the
Umut Atakan Gurkan et al.
Advanced healthcare materials, 1(5), 661-668 (2012-11-28)
Stimuli responsive, smart interface materials are integrated with microfluidic technologies creating new functions for a broad range of biological and clinical applications by controlling the material and cell interactions. Local capture and on-demand local release of cells are demonstrated with
Avraham Halperin et al.
Langmuir : the ACS journal of surfaces and colloids, 28(48), 16623-16637 (2012-11-06)
Thermoresponsive tissue culture substrates based on PNIPAM brushes are used to harvest confluent cell sheets for tissue engineering. The prospect of clinical use imposes the utilization of culture medium free of bovine serum, thus suggesting conjugation with adhesion peptides containing
A C C Rotzetter et al.
Advanced materials (Deerfield Beach, Fla.), 24(39), 5352-5356 (2012-08-31)
Buildings can be effectively cooled by a bioinspired sweating-like action based on thermoresponsive hydrogels (PNIPAM), which press out their stored water when exceeding the lower critical solution temperature. The surface temperature is reduced by 15 °C compared to that of
Jinseok Byun et al.
Chemical communications (Cambridge, England), 48(74), 9278-9280 (2012-08-09)
We report a novel approach for the fabrication of a photo-responsive surface with fast and reversibly switchable wettability between hydrophobicity and hydrophilicity induced by a photothermal effect.
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Universal Platform for Surface Modification Employing Grafted Polymer Layers

The present publication focuses on synthesis and characterization of nanothick, chemically grafted polymer films (polymer brushes) on various inorganic and polymeric substrates.

Universal Platform for Surface Modification Employing Grafted Polymer Layers

The present publication focuses on synthesis and characterization of nanothick, chemically grafted polymer films (polymer brushes) on various inorganic and polymeric substrates.

Universal Platform for Surface Modification Employing Grafted Polymer Layers

The present publication focuses on synthesis and characterization of nanothick, chemically grafted polymer films (polymer brushes) on various inorganic and polymeric substrates.

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