371130

1,4-Diisocyanatobutane

97.0%

• Synonyme(s) : Tetramethylene diisocyanate
• Formule linéaire : OCN(CH₂)₄NCO
• Numéro CAS: 4538-37-8
• Poids moléculaire : 140.14
• Numéro Beilstein : 1756894
• Numéro MDL: MFCD00075559
• Code UNSPSC : 12162002
• ID de substance PubChem : 24863093
• Nomenclature NACRES : NA.23

Propriétés

• Niveau de qualité: 200
• Pureté: 97.0%
• Forme: liquid
• Point d'ébullition: 102-104 °C/14 mmHg (lit.)
• Densité: 1.105 g/mL at 25 °C (lit.)
• Température de stockage: 2-8°C
• Chaîne SMILES: O=C=NCCCCN=C=O
• InChI: 1S/C6H8N2O2/c9-5-7-3-1-2-4-8-6-10/h1-4H2
• Clé InChI: OVBFMUAFNIIQAL-UHFFFAOYSA-N

Description

Description générale

1,4-Diisocyanatobutane is a highly reactive compound with two isocyanate (-NCO) groups separated by a butane chain. It can undergo reactions such as urethane formation, crosslinking, and chain extension. It is widely used as a building block to synthesize polyurethane-based materials with excellent flexibility, impact resistance, and mechanical properties, making them useful in tissue engineering, contact lenses, biocompatible coatings, adhesives, foams, elastomers, and sealants.

Application

1,4-Diisocyanatobutanecan be used in the following fields:

Tissue engineering -As a precursor to synthesize polyurethane composites which can be used as 3D scaffolds for tissue engineering,

Contact lenses- As a cross-linking agent to prepare inorganic-organic hydrogel contact lenses for high refractive index ocular refractive correction biomaterial,

Controlled drug delivery- As a chain extender to synthesize segmented polyurethanes for redox-sensitive controlled drug release systems.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H302 + H312 + H332,H315,H317,H319,H334,H335
• Conseils de prudence: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 222.8 °F - closed cup
• Point d'éclair (°C): 106 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter