274666

Thymoquinone

≥98%

• Synonyme(s) : 2-Isopropyl-5-methyl-1,4-benzoquinone
• Formule empirique (notation de Hill): C₁₀H₁₂O₂
• Numéro CAS: 490-91-5
• Poids moléculaire : 164.20
• Numéro CE : 207-721-1
• Numéro MDL: MFCD00001602
• Code UNSPSC : 12171500
• ID de substance PubChem : 24856596
• Nomenclature NACRES : NA.47

Propriétés

• Pureté: ≥98%
• Forme: solid
• Technique(s): titration: suitable
• Couleur: yellow
• Point d'ébullition: 230-232 °C (lit.)
• Pf: 45-47 °C (lit.)
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: CC(C)C1=CC(=O)C(C)=CC1=O
• InChI: 1S/C10H12O2/c1-6(2)8-5-9(11)7(3)4-10(8)12/h4-6H,1-3H3
• Clé InChI: KEQHJBNSCLWCAE-UHFFFAOYSA-N

Description

Description générale

Thymoquinone (TQ), also known as 2-isopropyl-5-methyl-1, 4-benzoquinone, is present in a crystalline triclinic form. It is the bioactive constituent of the volatile oil of black seed. TQ exhibits anti-inflammatory, antioxidant and anti-neoplastic effects both in vitro and in vivo.

Application

Thymoquinone has been used as an inhibitor of Escherichia coli ATP synthase and cell growth. It is also used as a drug against lower limb ischemia-reperfusion injury of the sciatic nerve and femoral muscle.
Thymoquinone is employed in preclinical studies as a neuroprotective and anticonvulsant agent.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 219.2 °F - closed cup
• Point d'éclair (°C): 104 °C - closed cup
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves