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202444

Sigma-Aldrich

Poly(éthylène glycol)

average MN 3,350, hydroxyl, powder

Synonyme(s) :

PEG

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About This Item

Formule linéaire :
H(OCH2CH2)nOH
Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352104
ID de substance PubChem :
Nomenclature NACRES :
NA.23

product name

Poly(éthylène glycol), average Mn 3,350, powder

Forme

powder

Niveau de qualité

Poids mol.

average Mn 3,350

pH

4.5-7.5

Viscosité

90 cSt(210 °F) (99 °C)(lit.)

Pf

54-58 °C (lit.)

Densité

1.204 g/mL at 25 °C

Extrémité Ω

hydroxyl

Extrémité α

hydroxyl

Chaîne SMILES 

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clé InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Description générale

Poly(ethylene glycol) (PEG) is a biocompatible inert synthetic polymer with repeating units of ether oxygen (-CH2-CH2-O-). It can be synthesized via anionic polymerization of ethylene oxide. It is extensively used in biological and medical applications due to its non-immunogenicity and high water solubility.

Application

PEG can be used to functionalize magnetite nanoparticles. The coating of the magnetic core with PEG provides good stabilization while maintaining the magnetic properties of the nanoparticles.

It can be used to modify the surface of photocatalytic TiO2 nanopowder for its application in self-cleaning paints. PEG-coated TiO2 nanopowder can be prepared under mild conditions and show excellent colloidal stability.

It can be used as a cross-linker to prepare poly(N-isopropylacrylamide) based thermosensitive injectable hydrogels. The addition of PEG improves the chemical and mechanical properties of hydrogel and prevents it from dissolving in the swelling medium. Owing to their biocompatibility and biodegradability, these hydrogels are widely used for biomedical applications.

Caractéristiques et avantages

  • High structural flexibility
  • Biocompatibility
  • High hydration capacity
  • Devoid of any steric hindrance

Autres remarques

Molecular weight: Mn 3,015-3,685

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Les clients ont également consulté

Grant A Robinson et al.
Journal of neuroscience research, 94(7), 636-644 (2016-03-21)
Functional recovery following a peripheral nerve injury is made easier when regenerating axons correctly reinnervate their original targets. Polyethylene glycol (PEG) has recently been used in attempts to fuse severed peripheral axons during suture-based repair, but an analysis of target
Erinna F Lee et al.
Autophagy, 15(5), 785-795 (2019-01-11)
BECN1/Beclin 1 is a critical protein in the initiation of autophagosome formation. Recent studies have shown that phosphorylation of BECN1 by STK4/MST1 at threonine 108 (T108) within its BH3 domain blocks macroautophagy/autophagy by increasing BECN1 affinity for its negative regulators
Yixu Wang et al.
mSphere, 4(3) (2019-05-31)
Sporisorium scitamineum is the fungal pathogen causing severe sugarcane smut disease that leads to massive economic losses globally. S. scitamineum invades host cane by dikaryotic hyphae, formed after sexual mating of two haploid sporidia of opposite mating type. Therefore, mating/filamentation
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro

Articles

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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Contenu apparenté

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

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