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Key Documents

122262

Sigma-Aldrich

N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine

98%

Synonyme(s) :

Edetol, Entprol, (Ethylenedinitrilo)tetra-2-propanol, Quadrol®

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About This Item

Formule linéaire :
[CH3CH(OH)CH2]2NCH2CH2N[CH2CH(OH)CH3]2
Numéro CAS:
Poids moléculaire :
292.41
Numéro Beilstein :
1781143
Numéro CE :
Numéro MDL:
Code UNSPSC :
12162002
ID de substance PubChem :
Nomenclature NACRES :
NA.23

Pression de vapeur

1 mmHg ( 20 °C)

Niveau de qualité

Pureté

98%

Indice de réfraction

n20/D 1.4812 (lit.)

Point d'ébullition

175-181 °C/0.8 mmHg (lit.)

Densité

1.013 g/mL at 25 °C (lit.)

Chaîne SMILES 

CC(O)CN(CCN(CC(C)O)CC(C)O)CC(C)O

InChI

1S/C14H32N2O4/c1-11(17)7-15(8-12(2)18)5-6-16(9-13(3)19)10-14(4)20/h11-14,17-20H,5-10H2,1-4H3

Clé InChI

NSOXQYCFHDMMGV-UHFFFAOYSA-N

Description générale

N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine (also known as Quadrol) is an ethylenediamine based monomer used in the production of polyurethane coatings, adhesives, cosmetics and personal care products. It can act as a chelating agent, due to the presence of its four hydroxyl groups, and a crosslinking agent, due to its two amino groups. It is widely used as a building block for polymers and copolymers, particularly those that are designed for use in UV-cross linkable polyurethane polymers, dendritic amino polymers, conducting polymers, inks, and coatings. Additionally, Quadrol is used in the production of resins, as well as in the manufacture of surfactants, plasticizers, and other chemical products.

Application

N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine can be used as:
  • A monomer in the synthesis of covalently cross-linked and amorphous shape memory polyurethane (SMPU) foams that are used in biomedical applications, which includes SMPU actuators for treating ischemic stroke, thrombus removal activated by laser light, self-deployable SMP neuronal electrodes, vascular stents, sutures in microsurgery, ocular implants, bandages, cell manipulation, and cell therapy.
  • A precursor in the preparation of self-healing CFRPs (carbon fiber reinforced polymer) which are thermally responsive with excellent mechanical properties.
  • A crosslinking agent to create a hydrogel that is biocompatible and supports the growth of neural cells. Hydrogels are specifically designed to mimic the properties of the extracellular matrix (ECM), in promoting cell proliferation. The purpose of the hydrogel in this context is to act as an extracellular matrix (ECM) substitute, providing a supportive environment for cell growth and guiding cell adhesion and outgrowth. This study investigates the potential of the peptide-modified channels to facilitate neural tissue engineering and enhance cell proliferation within the hydrogel-based scaffold.

Informations légales

Quadrol is a registered trademark of BASF Corporation

Pictogrammes

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Mention d'avertissement

Warning

Mentions de danger

Conseils de prudence

Classification des risques

Eye Irrit. 2

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

411.8 °F - closed cup

Point d'éclair (°C)

211 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves


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Consulter la Bibliothèque de documents

Thermally responsive self-healing composites with continuous carbon fiber reinforcement
Yunseon Heo and Henry A. Sodano
Composites Science and Technology, 118, 244-250 (2015)
Ona Gyliene et al.
Journal of hazardous materials, 175(1-3), 452-459 (2009-11-10)
Decontamination of solutions containing Cu(II) complexes with tartrate, glycine and quadrol (N,N,N'N'-tetrakis(2-hydroxypropyl)ethylenediamine) using metallic iron depends on pH and proceeds best in mildly acidic solutions. Cu(II) is completely removed from all solutions containing the ligands investigated. The degree of ligand
M V Bhide et al.
Journal of immunopharmacology, 7(3), 303-312 (1985-01-01)
Mouse peritoneal macrophages, when exposed to Quadrol [N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine] in vitro, show a dose dependent enhanced spreading over a four-hour period. In vitro Quadrol induced phagocytosis of polystyrene beads was found to be time and concentration dependent. The rate and extent
Low density biodegradable shape memory polyurethane foams for embolic biomedical applications
Pooja S, et al.
Acta Biomaterialia, 10(1), 67-76 (2014)
M J Dunphy et al.
Journal of chromatography, 488(2), 369-377 (1989-03-24)
A wide-bore capillary gas chromatographic method with nitrogen-selective thermionic detection is described for the quantitative analysis of N,N,N',N'-tetrakis (2-hydroxypropyl)ethylenediamine (Quadrol) in plasma. N,N,N',N'-tetrakis (2-hydroxybutyl)ethylenediamine is used as an internal standard. Rat or human plasma samples (0.5 ml) are mixed with

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