PLA0228

Rabbit anti-Ki-67 IHC Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): CAP, HUNK1, HUNKI, MCAP, Protein HUNK1, bromodomain-containing 4, chromosome-associated protein
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• grade: Powered by Bethyl Laboratories, Inc.
• species reactivity: mouse, human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry: 1:1,000-1:5,000; immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:2,000-1:10,000
• accession no.: NP_002408.2
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: human ... MKI67(4288)

Description

Immunogen

Antibody was affinity purified using an epitope specific to Ki-67 immobilized on solid support. The epitope recognized by PLA0228 maps to a region between residues 1800 and 1850 of human Ki-67 using the numbering given in entry NP_002408.2 (GeneID 4288).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

Ki-67 is a marker of cell proliferation detected in cells that are in G1-, S-, G2-, and M-phase of the cell cycle and absent in cells in G0. Ki-67 is detected exclusively in the nucleus, and its detection by immunohistological methods has proven to have diagnostic and prognostic value in the study of a variety of human tumors. The specific cellular functions of Ki-67 have not been elucidated, but it is proposed to function in the organization and maintenance of the architecture of DNA and in the synthesis of ribosomes during mitosis.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable