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31706

Supelco

Nitrofurazone solution

VETRANAL®, 100 μg/mL in acetonitrile, analytical standard

Synonym(s):

Nitrofural solution

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About This Item

Empirical Formula (Hill Notation):
C6H6N4O4
CAS Number:
Molecular Weight:
198.14
Beilstein:
1347298
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

2-8°C

SMILES string

NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O

InChI

1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

InChI key

IAIWVQXQOWNYOU-FPYGCLRLSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ryan W Benson et al.
PloS one, 6(5), e19944-e19944 (2011-05-27)
DinB (DNA Pol IV) is a translesion (TLS) DNA polymerase, which inserts a nucleotide opposite an otherwise replication-stalling N(2)-dG lesion in vitro, and confers resistance to nitrofurazone (NFZ), a compound that forms these lesions in vivo. DinB is also known
Prevention of CAUTI: simple is beautiful.
Marc Leone
Lancet (London, England), 380(9857), 1891-1892 (2012-11-09)
James R Johnson et al.
Antimicrobial agents and chemotherapy, 56(9), 4969-4972 (2012-07-04)
Two marketed antimicrobial-coated Foley catheters were compared for in vitro diffusible and contact-dependent inhibition of 11 urinary tract infection-associated microorganisms in an adherence-biofilm assay. Nitrofurazone-coated catheters significantly outperformed silver alloy-coated catheters for inhibitory activity, according to both inoculum broth and
Fengyu Deng et al.
Molecular bioSystems, 8(5), 1446-1451 (2012-02-18)
The interaction of nitrofurazone (NF) and human serum albumin (HSA) has been studied by fluorescence spectroscopy, FT-IR spectroscopy and molecular modeling methods. The results showed that the fluorescence of HSA was quenched by NF in a static quenching mechanism. Thermodynamic
Arnaud Gutierrez et al.
Nucleic acids research, 39(10), 4192-4201 (2011-02-09)
Escherichia coli SOS functions constitute a multifaceted response to DNA damage. We undertook to study the role of yafP, a SOS gene with unknown function. yafP is part of an operon also containing the dinB gene coding for DNA Polymerase

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