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D119806

Sigma-Aldrich

Maleic hydrazide

ReagentPlus®, 99%

Synonym(s):

1,2-Dihydro-3,6-pyridazinedione, 3,6-Dihydroxypyridazine, 3,6-Pyridazinediol

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About This Item

Empirical Formula (Hill Notation):
C4H4N2O2
CAS Number:
123-33-1
Molecular Weight:
112.09
Beilstein:
112223
EC Number:
204-619-9
MDL number:
MFCD00006665
UNSPSC Code:
12352100
PubChem Substance ID:
24893373
NACRES:
NA.22

product line

ReagentPlus®

Assay

99%

form

powder

autoignition temp.

707 °F

mp

299-301 °C (dec.) (lit.)

SMILES string

O=C1NNC(=O)C=C1

InChI

1S/C4H4N2O2/c7-3-1-2-4(8)6-5-3/h1-2H,(H,5,7)(H,6,8)

InChI key

BGRDGMRNKXEXQD-UHFFFAOYSA-N

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Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335,H341

Hazard Classifications

Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

572.0 °F - closed cup

Flash Point(C)

300 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Z Swietlińska et al.
Mutation research, 55(1), 15-30 (1978-01-01)
Since 1950, maleic hydrazide (MH) has been introduced into agriculture as a major commercial herbicide and a depressant of plant growth in numerous circumstances such as suppression of sprouting of vegetables and stored food crops, control of sucker growth on
Jolanta Juchimiuk et al.
Mutation research, 565(2), 129-138 (2005-01-22)
The presence of a large number of pollutants, including mutagenic agents in the environment is a problem of a major concern. Rapid progress in plant biotechnology, especially in the development of cell transformation methods, including the production of transformed roots
T J Haley
Journal of toxicology and environmental health, 2(5), 1085-1094 (1977-05-01)
The chemistry, metabolism, toxicology, mutagenicity, and carcinogenicity of maleic hydrazide have been reviewed. There is little doubt that this chemical is a mutagen and a carcinogen in cell cultures and animals, but no evidence is available on human carcinogenicity regardless
Jita Patra et al.
Mutation research, 581(1-2), 173-180 (2005-02-24)
Salicylic acid (SA), 0.01 mM, a signalling phytohormone, was tested for induction of adaptive response against genotoxicity of methyl mercuric chloride (MMCl), 0.013 mM; ethylmethane sulfonate (EMS), 2.5 mM, or maleic hydrazide (MH), 5 mM, in root meristem cells of
Anne-Sophie Foltête et al.
Chemosphere, 85(10), 1624-1629 (2011-09-13)
The Viciafaba root tip micronucleus test is one of the most employed plant genotoxicity assays, and has been used on various types of contaminated materials. This test has been standardized by AFNOR, the French member organization of ISO. However, this
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