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765473

Sigma-Aldrich

Gold nanoparticles

15 nm diameter, carboxylic acid functionalized, PEG 3000 coated, OD 50, dispersion in H2O

Synonym(s):

Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

material

PEG 3000

Quality Level

100

form

dispersion in H2O
nanoparticles

packaging

glass bottle of 1 mL

OD

50

diameter

15 nm

pH

6.0-8.0 (25 °C)

bp

100 °C (lit.)

solubility

water: miscible

density

1.00 g/cm3

λmax

520 nm

functional group

carboxylic acid

storage temp.

2-8°C

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General description

Carboxylic acid functionalized GNPs form conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

Application

The carboxylic acid group binds with various proteins and is used in targeted drug delivery and gene therapy.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

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