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Key Documents

O0250000

Oxprenolol hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(RS)-1-(2-Allyloxyphenoxy)- 3-isopropylamino-2-propanol

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About This Item

Empirical Formula (Hill Notation):
C15H23NO3 · HCl
CAS Number:
6452-73-9
Molecular Weight:
301.81
EC Number:
229-260-5
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

oxprenolol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C15H23NO3.ClH/c1-4-9-18-14-7-5-6-8-15(14)19-11-13(17)10-16-12(2)3;/h4-8,12-13,16-17H,1,9-11H2,2-3H3;1H

InChI key

COAJXCLTPGGDAJ-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Oxprenolol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Description
Pricing

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Antonella De Rossi et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 839(1-2), 6-11 (2005-12-21)
High sensitivity analysis of oxprenolol in spiked human urine has been performed by capillary zone electrophoresis (CZE) in ammonium formate buffer pH 2.5 using an uncoated capillary with 1cm length C18 on-capillary preconcentrator at the inlet side. The preconcentrator was
P R Bontchev et al.
Journal of inorganic biochemistry, 83(1), 25-30 (2001-02-24)
The complexation between copper(II) and the antihypertensive drug oxprenolol (HOxp) was studied both in methanol and slightly alkaline aqueous media at Cu:HOxp molar ratio from 1:1 to 1:10. Copper(lI) forms two types of complexes-a mononuclear violet one, CuOxp2, with bidentately
K Görlitzer et al.
Die Pharmazie, 59(10), 763-769 (2004-11-17)
The N-allyl derivatives 2 formed from the beta-blockers 1, were acetylated to give the esters 5. The 1,5-benzoxazacycloundecine 6a and the 1,10,5-benzodioxazacyclododecine 7a were isolated by ring closing metathesis (RCM) of 5a and 5b, respectively, using Grubbs catalyst in the
Erzsébet H Puhó et al.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 44(2), 194-202 (2007-03-03)
To evaluate the possible association between all kinds of drug treatments during pregnancy and isolated cleft lip with or without cleft palate (CL/P) and posterior cleft palate (PCP) in the offspring. The dataset of the large population-based Hungarian Case-Control Surveillance
M Nogowska
Acta poloniae pharmaceutica, 57(5), 353-357 (2000-12-29)
Stability of series of O-acyl esters of oxprenolol prepared as potential pro-drugs, is investigated over the pH range 0.4-10 at 37 degrees C. Maximum stability of all esters occurred at pH 3-4. The most stable derivative was found to be
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