1265402

Ethyl acetate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): EtOAc
• Linear Formula: CH₃COOC₂H₅
• CAS Number: 141-78-6
• Molecular Weight: 88.11
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749791
• MDL number: MFCD00009171
• Beilstein/REAXYS Number: 506104

Properties

• grade: pharmaceutical primary standard
• agency: USP
• vapor density: 3 (20 °C, vs air)
• vapor pressure: 73 mmHg ( 20 °C)
• form: liquid
• autoignition temp.: 801 °F
• expl. lim.: 2.2-11.5 %, 38 °F
• manufacturer/tradename: USP
• refractive index: n20/D 1.3720 (lit.)
• bp: 76.5-77.5 °C (lit.)
• mp: −84 °C (lit.)
• density: 0.902 g/mL at 25 °C (lit.)
• application(s): USP Biologics; pharmaceutical (small molecule); pharmaceutical
• format: neat
• SMILES string: CCOC(C)=O
• InChI: 1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
• InChI key: XEKOWRVHYACXOJ-UHFFFAOYSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Ethyl acetate, a volatile ester, is frequently employed in microbiology as a solvent and extraction agent. In the pharmaceutical and biologics industries, it is particularly useful in processes where a non-polar solvent is needed to extract bioactive compounds or for purification steps. Ethyl acetate is valued for its relatively low toxicity and efficient solvent properties, contributing to the formulation of biologic products while maintaining quality and compliance with regulatory standards.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ethyl acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

This product is part of USP Biologics Program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pha

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Codes: H225,H319,H336
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Central nervous system
• supp_hazards: EUH066
• Storage Class: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point (°F): 24.8 °F - closed cup
• Flash Point (°C): -4 °C - closed cup