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1229001

USP

Droperidol

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

1-[1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone

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About This Item

Empirical Formula (Hill Notation):
C22H22FN3O2
CAS Number:
548-73-2
Molecular Weight:
379.43
MDL number:
MFCD00083290
UNSPSC Code:
41116107
PubChem Substance ID:
329749689
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

droperidol

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Fc1ccc(cc1)C(=O)CCCN2CCC(=CC2)N3C(=O)Nc4ccccc34

InChI

1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28)

InChI key

RMEDXOLNCUSCGS-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

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Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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S Cure et al.
The Cochrane database of systematic reviews, (4)(4), CD002830-CD002830 (2004-10-21)
People suffering from acute psychotic illnesses, especially those associated with agitated or violent behaviour, may require urgent pharmacological tranquillisation or sedation. Droperidol, a butyrophenone neuroleptic, has been used for this purpose in several countries. To estimate the effects of droperidol
E S Brown et al.
Clinical neuropharmacology, 21(5), 316-318 (1998-10-28)
There is little information in the literature concerning the use of droperidol in psychiatry. This article presents three cases in which extremely agitated and treatment-refractory persons with mixed mania derived benefit from droperidol administered orally. Symptomatic improvement, including decreased agitation
I Henzi et al.
Canadian journal of anaesthesia = Journal canadien d'anesthesie, 47(6), 537-551 (2000-06-30)
To estimate the efficacy and harm produced by droperidol in the prevention of postoperative nausea and vomiting (PONV). Systematic search (MEDLINE, EMBASE, Cochrane library, hand-searching, bibliographies, all languages, up to May 1999) for randomised comparisons of droperidol with placebo in
Krzysztof Tracz et al.
British journal of clinical pharmacology, 79(4), 669-676 (2014-10-09)
Drugs used for postoperative nausea and vomiting prophylaxis are believed to provoke torsadogenic changes in cardiac repolarization. The aim of this study was to assess the effect of small doses of droperidol on the parameters of cardiac repolarization, including the
Droperidol- and ondansetron-induced life-threatening arrhythmias.
Jasmine Patel
Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association, 39(4), 393-394 (2013-07-09)
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