Discovery® C18 Supelguard Guard Cartridges [5 μm particle size, L × I.D. 2 cm × 4 mm] contain a Discovery® packing, in a 2 cm stainless steel body, enclosed by polyether ether ketone (PEEK) encapsulated stainless steel frits (2 μm porosity). A Supelguard kit (one cartridge, a stand-alone holder, tubing, and 2 nuts and ferrules) enables one to use the cartridge with any analytical column. A direct-connect guard cartridge holder can directly connect a Supelguard cartridge to a Supelco analytical column. 3.0 mm cartridges are available in packs of two only-purchase a stand-alone or modular holder separately. Low volume 3.0 mm ID cartridges are a good choice for protecting an analytical column containing 3 μm particles.
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Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
Journal of pharmaceutical and biomedical analysis, 38(1), 173-179 (2005-05-24)
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for application in rat in situ single pass intestinal perfusion study to assess intestinal permeability of
Journal of chromatography. A, 1095(1-2), 27-39 (2005-11-09)
The adsorption isotherms of an ionizable compound, nortriptyline, were accurately measured by frontal analysis (FA) on a C(18)-Discovery column, first without buffer (in an aqueous solution of acetonitrile at 15%, v/v of ACN), then with a buffer (in 28%, v/v
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(24), 2423-2429 (2011-07-26)
A novel isocratic reversed-phase high performance liquid-chromatography/ultraviolet detection method for simultaneous determination of cefdinir and cefixime in human plasma was developed and validated after optimization of various chromatographic conditions and other experimental parameters. Sample preparation based on a simple extraction
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 22(5), 483-487 (2014-12-05)
This study presents the optimization of a simple HPLC-UV method for the determination of metformin in human plasma. Ion pair separation followed by UV detection was performed on deproteinized human plasma samples. The separation was carried out on a Discovery
Journal of separation science, 32(9), 1312-1322 (2009-04-29)
Modafinil, adrafinil and their related substances were synthesized and analyzed by RP-LC with ESI-MS/MS. The ionization mode, polarity, cone voltage, and chromatographic conditions were evaluated. The optimum LC-MS conditions to obtain fragment ions indispensable for identification of the structures were
Discovery C18 and C8 HPLC Columns products offered
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