T5251

D-(+)-Trehalose dihydrate

≥98.5% (HPLC), from Saccharomyces cerevisiae

• Synonym(s): α,α-Trehalose dihydrate, D-Trehalose dihydrate, α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside
• Empirical Formula (Hill Notation): C₁₂H₂₂O₁₁ · 2H₂O
• CAS Number: 6138-23-4
• Molecular Weight: 378.33
• UNSPSC Code: 12352201
• NACRES: NA.25
• PubChem Substance ID: 57654674
• EC Number: 202-739-6
• Beilstein/REAXYS Number: 5322018
• MDL number: MFCD00071594

Properties

• biological source: Saccharomyces cerevisiae
• Quality Segment: 300
• assay: ≥98.5% (HPLC)
• form: powder
• optical activity: [α]/D 174 to 182 °, c = 1.0% (w/v) in water
• technique(s): HPLC: suitable, cryopreservation: suitable
• mp: 97-99 °C
• application(s): agriculture; cell analysis; genomic analysis; life science and biopharma
• SMILES string: [H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
• InChI key: DPVHGFAJLZWDOC-PVXXTIHASA-N

Description

General description

D-(+)-Trehalose, a disaccharide, acts as a chemical chaperone and serves as a carbohydrate reserve in microorganisms. It functions as an osmolyte, safeguarding cells against various environmental stresses[1]. Further, it also plays a crucial role in protein stabilization during freeze drying, making it a valuable asset in the areas of biochemical, cell culture, and excipient research

Application

• Use as a cryoprotectant in a variety of cell freezing media
• Used in excipeint research

Biochem/physiol Actions

Trehalose is a non-reducing sugar formed from two glucose units joined by a 1-1 alpha bond. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.

Features and Benefits

• Prepared from Saccharomyces cerevisiae
• Suitable for use with HPLC and GC-MS(4)

Preparation Note

Prepared by the modified procedure of Payen, R., Can. J. Res., 27B, 749 (1949).

Other Notes

For additional information on our range of Biochemicals, please complete this form.

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)