SML2483

Fesoterodine fumarate

≥93% (HPLC)

• Synonym(s): 2-Methylpropanoic acid-2-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl ester, fumarate salt
• Empirical Formula (Hill Notation): C₂₆H₃₇NO₃ · C₄H₄O₄
• CAS Number: 286930-03-8
• Molecular Weight: 527.65
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD12756004
• Assay: ≥93% (HPLC)
• Form: powder

Properties

• assay: ≥93% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(C(C)C)OC1=C([C@@H](C2=CC=CC=C2)CCN(C(C)C)C(C)C)C=C(CO)C=C1.OC(/C=C/C(O)=O)=O
• InChI: 1S/C26H37NO3.C4H4O4/c1-18(2)26(29)30-25-13-12-21(17-28)16-24(25)23(22-10-8-7-9-11-22)14-15-27(19(3)4)20(5)6;5-3(6)1-2-4(7)8/h7-13,16,18-20,23,28H,14-15,17H2,1-6H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t23-;/m1./s1
• InChI key: MWHXMIASLKXGBU-RNCYCKTQSA-N

Description

Biochem/physiol Actions

Fesoterodine fumarate is a prodrug of 5-hydroxymethyl tolterodine (5-HMT), which a muscarinic M2 and M3-receptor antagonist with antispasmodic activity, and is also the active metabolite of tolterodine. Fesoterodine fumarate is used clinically for the treatment of overactive bladder (OAB).

Muscarinic M2 and M3-receptor antagonist; Anti-spasmodic

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H319,H361d,H412
• pcodes: P202 - P264 - P273 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable