SML2213

CPI-637

≥98% (HPLC)

• Synonym(s): (4R)-1,3,4,5-Tetrahydro-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-2H-1,5-benzodiazepin-2-one, (4R)-4-Methyl-6-[1-methyl-3-(1-methylpyrazol-4-yl)indazol-5-yl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one, 2H-1,5-Benzodiazepin-2-one, 1,3,4,5-tetrahydro-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-, (4R)-, CPI 637
• Empirical Formula (Hill Notation): C₂₂H₂₂N₆O
• CAS Number: 1884712-47-3
• Molecular Weight: 386.45
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD30489741
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -39 to -49°, c = 1.0 in chloroform-d
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: [n]1(ncc(c1)c2n[n](c3c2cc(cc3)c4c5c(ccc4)NC(=O)C[C@H](N5)C)C)C
• InChI: 1S/C22H22N6O/c1-13-9-20(29)25-18-6-4-5-16(22(18)24-13)14-7-8-19-17(10-14)21(26-28(19)3)15-11-23-27(2)12-15/h4-8,10-13,24H,9H2,1-3H3,(H,25,29)/t13-/m1/s1
• InChI key: BFTKDWYIRJGJCA-CYBMUJFWSA-N

Description

Biochem/physiol Actions

CBP/p300 Bromodomain inhibitor

CPI-637 is a cell penetrant, selective and potent CBP/p300 bromodomain inhibitor.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable