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Key Documents

SAB2500760

Sigma-Aldrich

Anti-PCK2/PEPCK-M antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-HGNC:8725, Anti-PEPCK-M, Anti-PEPCK2, Anti-Phosphoenolpyruvate carboxykinase 2 (mitochondrial)

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About This Item

MDL number:
MFCD08460534
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

flow cytometry: suitable
immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable

UniProt accession no.

Q16822

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PCK2(5106)

General description

The gene encoding phosphoenolpyruvate carboxykinase 2, mitochondrial (PEPCK-M) or PCK2 is localized on human chromosome 14q11.2–q12.

Immunogen

Peptide with sequence KPWKPGDKEPCAH from the internal region of the protein sequence according to NP_004554.2.

Biochem/physiol Actions

Phosphoenolpyruvate carboxykinase 2, mitochondrial (PEPCK-M) or PCK2 has a role in gluconeogenesis and TCA cycle. It converts oxaloacetate to phosphoenolpyruvate. Elevated levels of this protein are observed in non-small-cell lung carcinoma (NSCLC).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Precautionary Statements

P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth.
Molecular Cell (2015)
Human mitochondrial phosphoenolpyruvate carboxykinase 2 gene
Said Modaressi
The Biochemical Journal (1998)
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth
Emma E.Vincent
Molecular Cell (2015)

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