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S3386

Sigma-Aldrich

Sorbitan sesquioleate

nonionic surfactant

Synonym(s):

Arlacel® 83, Span® 83

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.25

biological source

corn

vapor pressure

0.81 psi ( 20 °C)

form

liquid

refractive index

n20/D 1.478 (lit.)

density

0.989 g/mL at 25 °C (lit.)

functional group

ester

lipid type

oils

shipped in

ambient

storage temp.

room temp

SMILES string

OC[C@@H](O)C1OC[C@H](O)[C@H]1O.OC[C@@H](O)C2OC[C@H](O)[C@H]2O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/3C18H34O2.2C6H12O5/c3*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;2*7-1-3(8)6-5(10)4(9)2-11-6/h3*9-10H,2-8,11-17H2,1H3,(H,19,20);2*3-10H,1-2H2/b3*10-9-;;/t;;;2*3-,4+,5-,6-/m...11/s1

InChI key

SPFRYHCSFBFNTR-RKGWDQTMSA-N

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General description

Sorbitan sesquioleate (SSO) is a sorbitol derivative emulsifier. It is a common emulsifier component in topical corticosteroids, topical antibiotics, topical antifungals, moisturizing creams and lotions and topical retinoids.

Biochem/physiol Actions

Sorbitan sesquioleate is useful as a stabilizing agent in polymerization process to produce spherical acrylamide beads. It has been used in many topical agents. SSO have recently been implicated in allergic dermatitis.

Other Notes

Fatty acid composition: Oleic acid (C18:1) approx. 70%; balance primarily palmitic acid (C16:0), stearic acid (C18:0) and linoleic acid (C18:2).

Legal Information

Arlacel is a registered trademark of Croda International PLC
Span is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Allergic contact dermatitis to sorbitan sesquioleate in Adaptic wound dressing.
F B de Waard-van der Spek et al.
Contact dermatitis, 57(1), 54-56 (2007-06-20)
Sorbitan sesquioleate: an emerging contact allergen
Asarch A and Scheinman PL
Dermatitis : Contact, Atopic, Occupational, Drug : Official Journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group, 19(6), 339-341 (2008)
Allergic contact dermatitis to sorbitan sesquioleate in children.
Mari Paz Castanedo-Tardan et al.
Contact dermatitis, 58(3), 171-172 (2008-02-19)
Contact dermatitis due to emulsifiers.
F Pereira et al.
Contact dermatitis, 36(2), 114-114 (1997-02-01)
S Fukanoki et al.
The Journal of veterinary medical science, 62(6), 571-574 (2000-07-25)
The relationship between release properties of the model antigen, bovine serum albumin (BSA), from formulations in vitro and immune response after administration of various oil adjuvanted vaccines containing liquid paraffin was examined in chickens. The vaccine prepared at an hydrophile-lipophile-balance

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