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PZ0306

Sigma-Aldrich

PF-6808472

≥98% (HPLC)

Synonym(s):

4-{4-[4-(5-Cyclopropyl-1H-pyrazol-3-ylamino)-6-prop-2-ynylcarbamoyl-pyrimidin-2-yl]-piperazin-1-ylmethyl}-benzenesulfonyl fluoride, XO44

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About This Item

Empirical Formula (Hill Notation):
C25H27FN8O3S
CAS Number:
2088112-70-1
Molecular Weight:
538.60
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

−20°C

Biochem/physiol Actions

PF-6808472 is a cell permeable covalent probe suitable for click chemistry designated to measure kinase selectivity in intact cells. PF-6808472 contains sulfonyl fluoride group, which react with conserved lysine residue within kinase ATP binding site.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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