N1516

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid

chromogenic, ≥95%, powder

• Synonym(s): PNP-a-NeuNAc
• Empirical Formula (Hill Notation): C₁₇H₂₂N₂O₁₁
• CAS Number: 26112-88-9
• Molecular Weight: 430.36
• UNSPSC Code: 12352204
• PubChem Substance ID: 24897497
• NACRES: NA.32
• MDL number: MFCD00132944

Properties

• Product Name: 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid, ≥95%
• assay: ≥95%
• form: powder
• impurities: ~0.5% free p-nitrophenol
• solubility: methanol: 25 mg/mL, clear, colorless to faintly yellow
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: CC(=O)NC1C(O)CC(OC1C(O)C(O)CO)(Oc2ccc(cc2)N(=O)=O)C(O)=O
• InChI: 1S/C17H22N2O11/c1-8(21)18-13-11(22)6-17(16(25)26,30-15(13)14(24)12(23)7-20)29-10-4-2-9(3-5-10)19(27)28/h2-5,11-15,20,22-24H,6-7H2,1H3,(H,18,21)(H,25,26)
• InChI key: OICUZSPXIJAAEA-UHFFFAOYSA-N

Description

Application

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid may be used as a substrate to measure sialidase enzyme activity.

Biochem/physiol Actions

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid serves as a sialyl donor in enzyme-catalyzed trans-sialylation.

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 + H311 + H331,H315,H319,H335,H351
• pcodes: P202 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges