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G9753

Sigma-Aldrich

α-D-Glucosamine 1-phosphate

Synonym(s):

2-Amino-2-deoxy-α-D-glucopyranosyl phosphate

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About This Item

Empirical Formula (Hill Notation):
C6H14NO8P
CAS Number:
Molecular Weight:
259.15
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

natural (inorganic)

Assay

≥97% (TLC)

form

powder

impurities

<8.5% water (Karl Fischer)

color

white

solubility

water: 100 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

NC1C(O)C(O)C(CO)OC1OP(O)(O)=O

InChI

1S/C6H14NO8P/c7-3-5(10)4(9)2(1-8)14-6(3)15-16(11,12)13/h2-6,8-10H,1,7H2,(H2,11,12,13)

InChI key

YMJBYRVFGYXULK-UHFFFAOYSA-N

Application


  • Cellodextrin phosphorylase from Ruminiclostridium thermocellum: X-ray crystal structure and substrate specificity analysis. This study presents the enzymatic synthesis and analysis of alpha-ᴅ-Glucosamine 1-phosphate based polysaccharides using cellodextrin phosphorylase, showcasing potential for novel biomaterial development. Field et al., 2017

  • Glucose-1-phosphate uridylyltransferase from Erwinia amylovora: Activity, structure and substrate specificity. This paper explores the biochemical pathway involving alpha-ᴅ-Glucosamine 1-phosphate in the context of bacterial metabolism, providing insights into microbial biochemistry and potential targets for antibacterial therapy. Field et al., 2017

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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D Mengin-Lecreulx et al.
The Journal of biological chemistry, 271(1), 32-39 (1996-01-05)
Two different approaches to identify the gene encoding the phosphoglucosamine mutase in Escherichia coli were used: (i) the purification to near homogeneity of this enzyme from a wild type strain and the determination of its N-terminal amino acid sequence; (ii)
Amit Parikh et al.
Journal of molecular biology, 386(2), 451-464 (2009-01-06)
Identifying direct targets of kinases and determining how their activities are regulated are central to understanding how they generate biological responses. Genetic and biochemical studies have shown that Mycobacterium tuberculosis serine/threonine protein kinases PknA and PknB play a role in
K Takayama et al.
The Journal of biological chemistry, 258(12), 7379-7385 (1983-06-25)
We have determined the complete structure of a glycolipid (designated lipid X) previously found to accumulate in certain Escherichia coli mutants defective in phosphatidylglycerol synthesis (Nishijima, M., and Raetz, C.R.H. (1979) J. Biol. Chem. 254, 7837-7844). Based on fast atom
F Hatzack et al.
Journal of chromatography. B, Biomedical sciences and applications, 736(1-2), 221-229 (2000-02-17)
A simple and inexpensive high-performance thin-layer chromatography (HPTLC) method for the analysis of inositol mono- to hexakisphosphates on cellulose precoated plates is described. Plates were developed in 1-propanol-25% ammonia solution-water (5:4:1) and substance quantities as low as 100-200 pmol were
S Ambrosio et al.
Journal of biochemical and biophysical methods, 25(4), 237-244 (1992-12-01)
Galactosamine is quickly metabolized to galactosamine 1-phosphate in rats treated with this compound. An HPLC method to quantify hexosamine phosphates in biological samples is described, modified from the o-phthaldialdehyde amino acid analysis procedure. o-Phthaldialdehyde derivatives of hexosamines and hexosamine-phosphates can

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