D3943

DAPH

≥98% (HPLC), solid

• Synonym(s): 4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411
• Empirical Formula (Hill Notation): C₂₀H₁₅N₃O₂
• CAS Number: 145915-58-8
• Molecular Weight: 329.35
• NACRES: NA.77
• PubChem Substance ID: 24724461
• UNSPSC Code: 51111800
• MDL number: MFCD00236442
• Assay: ≥98% (HPLC)
• Form: solid

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• color: orange
• solubility: DMSO: >20 mg/mL, H₂O: insoluble
• storage temp.: 2-8°C
• SMILES string: O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc4ccccc4)cc12
• InChI: 1S/C20H15N3O2/c24-19-15-11-17(21-13-7-3-1-4-8-13)18(12-16(15)20(25)23-19)22-14-9-5-2-6-10-14/h1-12,21-22H,(H,23,24,25)
• InChI key: AAALVYBICLMAMA-UHFFFAOYSA-N
• Gene Information: human ... EGFR(1956)

Description

Biochem/physiol Actions

DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR.

Features and Benefits

This compound is featured on the EGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)